Biostatistics and Data Management Core

德克萨斯大学生物统计学和数据管理核心。安德森癌症中心 白血病孢子将是一个全面的，多边的数据采集和管理资源， 设计实验室实验和临床试验，开发创新的统计方法， 统计分析，并发表通过白血病孢子计划产生的转化研究。 生物统计学和数据管理核心将在所有实验中纳入合理的实验设计原则。 项目，将使用适当的统计方法进行数据分析，并将有助于 通过书面报告和与项目调查人员的频繁互动来解释结果。的 生物统计和数据管理核心将提供一个综合数据管理系统， 所有项目和核心之间的沟通，这将是定制的，以满足需求的 白血病科。这一过程包括前瞻性数据收集、数据质量控制、数据 安全和病人隐私因此，从开始到报告，翻译实验将受益 从SPORE资源，将用于增加现有的M。D.安德森生物统计资源。 奠定摘要：服务于所有拟议的SPORE项目，以及职业发展和 发展研究计划，生物统计学和数据管理核心有以下内容 目标： * 在实验室实验和临床试验的设计和实施方面提供生物统计专业知识 由本申请中提出的研究产生 * 对在SPORE项目下收集的所有数据进行统计分析和解释， 开发项目和其他核心 * 提供可靠的数据捕获和存储功能，面向用户的检索能力，以及有效的 确保患者保密性的机制

The Biostatistics and Data Management Core for the University of Texas M.D. Anderson Cancer Center Leukemia SPORE will be a comprehensive, multilateral resource for data acquisition and management, design of laboratory experiments and clinical trials, development of innovative statistical methodology, statistical analysis, and publishing translational research generated through the Leukemia SPORE program. The Biostatistics and Data Management Core will incorporate sound experimental design principles within all Projects, will carry out data analyses using appropriate statistical methodology, and will contribute to interpretation of results through written reports and frequent interaction with Project investigators. The Biostatistics and Data Management Core will provide an integrated data management system to facilitate communication among all Projects and Cores, which will be customized to meet the needs of the Department of Leukemia. This process includes prospective data collection, data quality control, data security, and patient confidentiality. Thus, from inception to reporting, translational experiments will benefit from SPORE resources that will be used to augment existing M. D. Anderson biostatistics resources. Lay abstract: To serve all proposed SPORE projects, as well as the Career Development and Developmental Research Programs, the Biostatistics and Data Management Core has the following objectives: *Provide biostatistical expertise in the design and conduct of laboratory experiments and clinical trials arising from the research proposed in this application *Provide statistical analysis and interpretation of all data collected under the SPORE Projects, Developmental Projects, and other Cores *Provide reliable data capture and storage functions, user-oriented retrieval capability, and effective mechanisms for ensuring patient confidentiality