Impact of Core Implementation Components on Adoption

近年来，美国国家药物滥用研究所（NIDA）临床试验网络（CTN） 在测试有希望的成瘾治疗的有效性和传播研究结果方面取得了重大进展 关于那些治疗的事与此同时，全国范围内的药物滥用治疗系统面临着一种趋势， 越来越多地使用基于证据的实践。在这些相辅相成的努力中， 在这一趋势下，翻译研究成果以满足实践需要的问题日益突出。一些 理论观点和结构已经提出，但建立他们的有用性提供了单一的 由于被认为影响研究翻译的因素范围，以及项目和 需要长时间的视野来评估研究翻译成果。作为转化研究的实验室， 在与Ureal world”社区诊所合作进行研究的情况下，CTN允许观察 随着时间的推移，有效性研究的过程，从方案概念化到实施， 进入后期学习阶段。在与CTN协议0031（兴奋剂滥用团体参与12步： 第12阶段），本研究将评估与将研究转化为实践相关的关系： STAGE-12实施的保真度如何影响客户结果，B）是否通常假设 辅导员和组织变量影响治疗的保真度，以及c）在治疗中接受第12阶段干预。 试验结束后，参加的诊所。在探索性分析中，该项目将模拟这些多重 临床试验结束后，它们对干预措施采用的影响。尽管先前的研究 研究了这些变量之间的个体关系，本研究将评估这些变量中的多种关系。 在多中心临床试验的背景下，将观察范围扩展到实施前， 执行和执行后的措施和结构。该项目的短期目标是 在理论驱动的实施模型中评估关键关系，使用CTN STAGE-12研究， 一个研究平台16 ng的目标是加快CTN研究结果的转化， 实施，以便诊所可以更容易地采用基于研究的干预措施， 他们所服务的人、家庭和社区。

In recent years the National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) has made significant gains in testing the effectiveness of promising addiction treatments, and disseminating findings about those treatments to the field. At the same time, drug abuse treatment systems nationwide face a trend toward the increasing use of evidence-based practices. In the context of these complimentary efforts and trends, the translation of research findings to meet practice needs has gained prominence. A number of theoretical perspectives and constructs have been advanced, yet establishing their usefulness offers singular challenge due to the range of factors thought to impact research translation, and the number of programs and long time horizon needed to assess research translation outcomes. As a laboratory for translational research, where studies are conducted in partnership with Ureal world" community clinics, the CTN allows observation of the process of effectiveness research over time, from protocol conceptualization through implementation and into the post-study period. In collaboration with CTN protocol 0031 (Stimulant Abuser Groups to Engage in 12Step: STAGE-12), this study will assess relationships relevant to the translation of research into practice: a) how the fidelity of STAGE-12 implementation impacts client outcomes, b) whether commonly hypothesized counselor and organizational variables affect treatment fidelity, and c) uptake of the STAGE 12 intervention in participating clinics after the trial ends. In exploratory analyses, the project will model these multiple relationships for their impact on intervention adoption after the clinical trial ends. Although prior research has examined individual relationships among these variables, this study will assessing multiple relationships in the context of a multi-site clinical trial, extending observation to encompass pre-implementation, during implementation, and post implementation measures and constructs. The short term goal of the project is to assess key relationships in a theoretically driven model of implementation, using the CTN STAGE-12 study as a research platform. The 16ng term goal is to speed the translation of CTN research findings to implementation, so that clinics can more readily adopt research based interventions, and more effectively treat the persons families, and communities they serve.