NCCU-BBRI/UNC-LINEBERGER PARTNERSHIP IN CANCER RESEARCH

朱利叶斯湖北卡罗来纳州中央大学的钱伯斯生物医学生物技术研究所（Chambers Biomedical Biotechnology Research Institute，简称CHLCCC）和查佩尔山的北卡罗来纳州大学的林伯格综合癌症中心（Hellineberger Comprehensive Cancer Center，简称UNC-CH）提议继续在癌症研究方面建立有效、可持续和互利的伙伴关系，重点关注非洲裔美国人的健康差异。在过去一年中，在国家癌症研究所的资助下，这两个机构通过建立互补的机构优势，在分子和人口科学方面进行联合规划，并强调一个具体可行的“门户”倡议，建立了一个NCCU癌症核心实验室，用于癌症研究的分子/遗传分析。该伙伴关系现在提议通过国家癌症研究所资助的合作规划赠款（U 56）扩大其倡议，用于综合少数民族机构/癌症伙伴关系。除了在分子/遗传分析和癌症核心实验室方面继续努力外，该伙伴关系还将强调一系列相互联系的门户试点倡议，并辅之以技术转让，从而促成一个重大的合作研究项目（包括外联/健康教育部分），即对非洲裔美国男子前列腺癌进行以人口为基础的队列研究。该项目将是计划申请综合少数民族机构/癌症中心合作伙伴关系（U 54 CMI/CCP）赠款的主要重点。该提案的具体合作内容包括：两个试点研究项目（检测开发和队列开发）;一个推广和教育试点计划;以JLC-BBRI癌症核心实验室为中心的资源和基础设施增强;以及初级教师和学生的职业发展。Lineberger和北卡罗来纳大学教堂山分校提供的伙伴关系：1）广泛的经验，专业知识和资源，癌症研究和培训;和2）在少数民族健康差距表现出兴趣。JLC-BBRI和NCCU提供的伙伴关系：1）通过文化上适当和敏感的干预措施接触少数群体的经验和专业知识; 2）接触少数群体的机会;和3）对少数民族学生可能感兴趣的职业生涯在癌症研究的培训机会。这些互补的机构优势将有助于伙伴关系：1）建立有效的癌症研究基础设施/计划，并增加少数民族服务机构的培训机会; 2）加强以社区和人口为基础的研究，针对少数民族癌症相关的健康差异，并增加NCI资助的硬币综合癌症中心的少数民族科学家的培训。

The Julius L. Chambers Biomedical Biotechnology Research Institute (UNC LCCC) at North Carolina Central University (NCCU) and the UNC Lineberger Comprehensive Cancer Center (UNC LCCC) at the University of North Carolina at Chapel Hill (UNC-CH) propose to continue an effective, sustainable, and mutually beneficial partnership in cancer research that focuses on African-American health disparities. During the past year and with funding from the National Cancer Institute, the two institutions have firmly established the Partnership by building on complementary institutional strengths conducting joint planning in the molecular and population sciences, and emphasizing a concrete and feasible "gateway" initiative: establishment of an NCCU Cancer Core Laboratory for molecular/genetic analysis in cancer research. The Partnership now proposes to expand its initiatives through an NCI-funded Cooperative Planning Grant (U56) for Comprehensive Minority Institution/Cancer Partnership. In addition to continued efforts in molecular/genetic analysis and the Cancer Core Laboratory, the Partnership will emphasize a series of linked gateway pilot initiatives, accompanied by technology transfer, that lead toward a major collaborative research project (with outreach/health education components) a population-based cohort study of prostate cancer in African-American men. This project will be a major focus of the planned application for a Comprehensive Minority Institution/Cancer Center Partnership (U54 CMI/CCP) grant. Specific collaborative components of the proposal include: two pilot research projects (assay development and cohort development); a pilot program in outreach and education; resource and infrastructure enhancement centering on the JLC-BBRI Cancer Core Laboratory; and career development for junior faculty and students. The UNC Lineberger and UNC-Chapel Hill offer the Partnership: 1) extensive experience, expertise, and resources for cancer research and training; and 2) a demonstrated interest in minority health disparities. The JLC-BBRI and NCCU offer the Partnership: 1) experience and expertise in reaching minority populations through culturally appropriate and sensitive interventions; 2) opportunities to access minority populations; and 3) training opportunities for minority students potentially interested in careers in cancer research. These complementary institutional strengths will help the Partnership: 1) establish an effective cancer research infrastructure/program and increase training opportunities at a minority serving institution; and 2) enhance community- and population-based research targeting minority cancer-related health disparities and increase training of minority scientists at an NCI funded Coin comprehensive Cancer Center.