DRUG INTERACTIONS AND BIOAVAILABILITY OF CRANBERRY FLAVANOIDS

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究由NIH/NCCAM申办。 众所周知，蔓越莓汁和粉末被公众用作治疗尿路感染和其他目的的替代药物。 蔓越莓汁和粉末含有大量的天然化学物质称为类黄酮。 这项研究的目的之一是确定大量摄入蔓越莓汁后血液和尿液中黄烷类化合物的浓度。 另一个目标是确定服用蔓越莓粉是否会影响其他处方药的分解和排泄（代谢），当蔓越莓粉与这些药物一起服用时。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is sponsored by NIH/NCCAM. It is known that cranberry juice and powders are being used by the general public as alternative medication to treat urinary tract infections and for other purposes. Cranberry juice and powders contain large quantities of natural chemicals called flavanoids. One of the goals of this study is to determine the concentrations of flavanoids in blood and urine after a large serving of cranberry juice is ingested. Another goal is to determine if taking a cranberry powder will affect the breakdown and excretion (metabolism) of other prescription medications when cranberry powder is taken together with these medications.