EVAL OF PLANT STEROL ESTER & PLACEBO ON LOW-DENSITY LIPOPROTEIN CONCENTRATIONS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 已有研究表明，降低胆固醇可以减少心脏病发作和死亡。在美国，有许多药物可以降低胆固醇。一些药物会被人体吸收，并与其他药物发生药物相互作用。然而，一些药物可以降低胆固醇，但不会被人体吸收。最近，美汁源公司在美国销售了一种降低胆固醇的橙汁。这项研究的目的是更好地了解降胆固醇药物Welchol？与降胆固醇橙汁(美汁源心脏智慧)联合使用对高胆固醇男性和女性的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Lowering cholesterol has been shown to reduce heart attacks and deaths related to heart disease. There are many medications available in the U.S. to lower cholesterol. Some medications are absorbed into the body and cause drug interactions with other medications. However, some medications lower cholesterol without being absorbed into the body. Recently, orange juice that lowers cholesterol has been marketed in the U.S. by the Minute Maid Corporation. The goal of this study is to better understand the effects of the cholesterol-lowering drug Welchol¿, which is not absorbed into the body, in combination with cholesterol-lowering orange juice (Minute Maid Heart Wise¿) in men and women with high cholesterol.