Core Grant for Vision Research

描述（由申请人提供）：纽约大学神经科学中心是研究视觉功能方面的主要场所。来自该中心的18名研究人员要求通过继续核心资助来支持他们的视力研究。他们的研究兴趣是视觉和视觉引导行为的神经和行为基础。拟议的核心将包括四个模块，每个模块都将有利于由项目教师代表的研究领域的研究：1。一个视觉显示模块，它将为开发最先进的软件提供支持，以生成各种各样的视觉刺激，用于心理物理学、神经生理学和大脑实验。2.一个设计和制造模块，将提供专业知识，设计和建立新的电子和机械设备，如在视觉皮层多电极记录所需的theose，眼动记录的非侵入性方法，以及行为和blloglcal实验的接口设备。3.一个神经解剖学和分子生物学模块，它将为在光和EM水平上处理神经解剖学材料、分析和定位组织学材料中的电生理记录部位以及创建含转基因病毒以实验性地修改神经元功能提供专家支持。4.一个功能成像模块，将为西门子MRI扫描仪和脑成像中心相关设备的用户提供硬件和软件服务支持，使核心研究人员能够访问人类和动物研究的功能和结构成像功能。

DESCRIPTION (provided by applicant): The Center for Neural Science at New York University is a premier site for research on functional aspects of vision. Eighteen investigators from the Center request support for their vision research through continuation of a Core Grant. They are bound together by their research Interests In the neural and behavioral bases of vision and visually guided behavior. The proposed Core will comprise of four modules, each of which will benefit research in the research areas represented by program faculty: 1. A Visual Displays Module which will provide support for the development of state-of-the-art software for the generation of a wide variety of visual stimuli for psychophysical, neurophysiological, and brain experiments. 2. A Design and Fabrication Module which will provide expertise to design and build novel electronic and mechanical devices such as theose required for multielectrode recording in the visual cortex, noninvasive methods of eye movement recording, and Interface devices for behavioral and blloglcal experiments. 3. A Neuroanatomy and Molecular Biology Module which will provide expert support for the processing of neuroanatomlcal material at both the light and EM level, for the analysis and localization of electrophysiological recording sites In histological material, and for the creation of transgene-containing viruses to modify neuronal funtlon experimentally. 4. A Functional Imaging Module which will provide support for hardware and software services for users of the Siemens MRI scanner and associated devices In the Center for Brain Imaging, giving access for Core researchers to functional and structural Imaging capabilities for human and animal research.