Curricular and Pedagogical Innovations in Quantitative Biology

说明应用程序的广泛、长期目标和具体目标，并提及与健康相关的 项目(即与该机构使命的相关性)。简明扼要地描述实现这些目标的研究设计和方法。描述 你将用来追求这些目标的基本原理和技术。 此外，用两三句简单明了的话描述这项研究与公共卫生的相关性。如果应用程序得到资助，则此 原样的描述将成为公开信息。因此，不包括专有/机密信息。不要超过空格 但前提是。 目前的本科生物科学课程没有提供足够的计算/定量 为有志于从事生物医学研究的学生提供培训。亨特大学 纽约城市大学(CUNY)将通过扩大和实施 生物学及相关科学的课程改革始于其名为 数量生物学(QUBI)倡议。曲壁跨学科教职员工小组的首要目标是整合 将计算和定量生物学内容分成26门不同的课程，提供约6,500门课程 每年注册的学生涉及生物、化学、计算机科学、数学和统计学 各部门。其中几门修改后的课程将向我们的本科生介绍 生物信息学，曲比预计每年将有多达20名学生学习新的生物信息学 在第一阶段开发的选项和浓度Qubi的第二个目标是建立一个持久的 通过培训我们的科学教员，为亨特培养数量生物学家提供教育基础设施 新的教学方法，如基于问题的学习(PBL)、协作课程开发和 协作式教学。我们的教职员工将参加教育会议和暑期工作坊。 由教育学专家运营。在这项计划中获得的所有知识将与 亨特曲壁的第三个目标是培养足够数量的数量生物学学生，这是成功的关键 二期工程。曲比团队将与学院现有的成功的科学相关人员合作 面向学生拓展的教育项目(MARC、MBRS/RISE、HHMI、NSF CSEMS和CollegeNow)，网址为 高中和大学阶段都是如此。亨特拟议的课程改革取得了成功 大学将对增加受过量化培训的生物学家的数量产生重大影响--特别是 少数民族科学家-在亨特和整个CUNY，因为亨特的课程活动将与 纽约州立大学的其他校园。 与公共卫生的相关性。今天可获得的生物信息量，如人类基因组 序列和健康统计数据正在呈指数级增长。计算科学和定量科学是 因此，在疾病预防和治疗中发挥着越来越重要的作用。拟议中的项目 将培养出具有生物医学研究所需的量化技能的下一代科学家 21世纪。 性能

State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project (i.e., relevance to the mission of the agency). Describe concisely the research design and methods for achieving these goals. Describe the rationale and techniques you will use to pursue these goals. In addition, in two or three sentences, describe in plain, lay language the relevance of this research to public health. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT EXCEED THE SPACE PROVIDED. Current undergraduate biological sciences curricula do not provide adequate computational/quantitative training for students who are interested in pursuing a career in biomedical research. Hunter College of the City University of New York (CUNY) will address this lack of training by broadening and implementing a curricular transformation in biology and related sciences begun during its Phase I project, named the Quantitative Biology (QuBi) initiative. QuBi's interdisciplinary faculty panel's first aim will integrate computational and quantitative biology content into 26 different courses serving approximately 6,500 registrants per year across the Biology, Chemistry, Computer Science, Mathematics and Statistics departments. Several of these modified courses will introduce our undergraduates to the field of bioinformatics, and QuBi anticipates that up to 20 students per year will pursue the new bioinformatics options and concentrations developed during Phase I. QuBi's second aim is to establish an enduring educational infrastructure for producing quantitative biologists at Hunter by training our science faculty in new pedagogical approaches such as problem-based learning (PBL), collaborative course development and collaborative teaching. Our faculty will attend educational conferences and participate in summer workshops run by pedagogical experts. All knowledge acquired during this initiative will be shared with faculty across Hunter. QuBi's third aim, to build a critical mass of quantitative biology students, is vital for the success of the Phase II project. The QuBi team will collaborate with the College's existing successful science-related educational programs (MARC, MBRS/RISE, HHMI, NSF CSEMS and CollegeNow) for student outreach at both the high school and the college level. The success of the proposed curricular transformation at Hunter College will have a major impact in increasing the number of quantitatively trained biologists - especially minority scientists - at Hunter and across CUNY, since the Hunter curricular activities will be shared with other CUNY campuses. Relevance to Public Health. The amount of biological information available today, such as human genome sequences and health statistics, is increasing exponentially. The computational and quantitative sciences are therefore playing an increasingly important role in disease prevention and treatment. The proposed project will produce a future generation of scientists with the quantitative skills required for biomedical research in the 21st century. PERFORMANCE