UCLA Older Americans Independence Center

加州大学洛杉矶分校克劳德·佩珀老年美国人独立中心(OAIC)旨在促进旨在维护和恢复老年人独立性的研究。通过其翻译研究保持独立性的主题，加州大学洛杉矶分校的OALC的研究跨越了从T1到T2的翻译研究的全范围。在这一主题中，加州大学洛杉矶分校OAIC的一个重要重点是开发和了解减少炎症的干预措施。 为了实现其目标，加州大学洛杉矶分校OAIC建立了4个研究核心(招聘和保留、研究运作、分析和成本效益以及炎症生物学)和一个新的信息传播核心，该核心将在每个步骤(招聘、测量、数据管理、分析、解释和采用研究结果)促进与OALC相关的研究。研究核心在4个层面上提供支持： 咨询(例如，提供长达数小时的建议、阅读一篇论文或一份提案) 短期(例如，最多几天的咨询、执行化验) 持续的或长期的支持(例如，持续的、项目团队的一部分) 就新提案建立伙伴关系 此外，加州大学洛杉矶分校OAIC飞行员和探索性研究核心和研究职业发展核心通过初级研究人员和飞行员奖项的渠道激励新的研究，并招募成功的研究人员参与OALC相关研究。该中心的一个具体目标是创建翻译研究团队，并培训初级教职员工，使他们掌握连接基础、临床和卫生服务/传播研究的研究原则。领导/行政核心确保完成这些具体活动，并以最佳方式实现加州大学洛杉矶分校OAIC的目标。 通过OAIC集中努力和资源，可以加快研究开发、测试和传播有希望的创新以保持独立性的时间表。在为期5年的周期结束时，加州大学洛杉矶分校的OAIC将成为从基础科学延伸到临床实践和政策的转化研究的典范项目，并将培养出一代新的研究人员，他们可以开始在这一主题上发挥领导作用。

The UCLA Claude Pepper Older Americans Independence Center (OAIC) is designed to promote research aimed at maintaining and restoring the independence of older persons. Through its theme of Translational Research to Maintain Independence, the UCLA OAlC's research extends across the full spectrum from T1 to T2 translational research. Within this theme, an important focus of the UCLA OAIC is on developing and understanding interventions that reduce inflammation. To accomplish its goals, the UCLA OAIC has established 4 Research Cores (Recruitment and Retention, Research Operations, Analysis and Cost Effectiveness, and Inflammatory Biology) and a new Information Dissemination Core that will facilitate OAlC-related research at every step (recruitment, measurement, data management, analysis, interpretation, and adoption of findings). Research cores provide support at 4 levels: Consultation (e.g., providing up to several hours of advice, reading a paper or a proposal) Short-term (e.g., up to a couple days of consultation, performing assays) Ongoing or long-term support (e.g., ongoing, part of the project team) Partnership on new proposals In addition, the UCLA OAIC Pilot and Exploratory Studies Core and Research Career Development Core stimulate new research via a pipeline of junior investigators and pilot awards and recruit successful investigators into OAlC-related research. A specific goal of the Center is to create teams of translational researchers and to train junior faculty in the principles of conducting research that bridges basic, clinical, and health services/dissemination research. The Leadership/Administrative Core ensures that these specific activities are accomplished and the goals of the UCLA OAIC are optimally achieved. By focusing efforts and resources through the OAIC, the timeline for research to develop, test, and disseminate promising innovations to maintain independence can be accelerated. At the end ofthe 5-year cycle, the UCLA OAIC will be a model program for translational research extending from basic science to clinical practice and policy and will have created a generation of new researchers who can begin to assume leadership in this theme.