Biostatistics and Data Coordinating Core (BDCC)

抽象核心C 核心C(生物统计和数据管理)的目标是在以下领域提供专家生物统计指导 设计、实施和分析构成计划项目的研究项目，并协助临床 调查人员正在开发可靠和准确的数据管理系统。核心C将提供生物统计学 在研究的各个阶段为研究项目提供支持。核心工作人员将与调查人员合作 制定有效的设计和样本大小，以提供足够的力量来实现研究目标。为 临床研究，我们将有助于设计病例报告表，以收集所有必要的信息在 毫不含糊的方式。随着研究的进行，核心工作人员将协助审查项目数据库并监测 收集的数据的数量和质量，并将对设计或分析计划提出修改建议，如下 恰如其分。核心成员将进行正确和高效的数据分析，准备任何必要的图表 和表格，协助调查人员准备演示文稿和手稿，并就 后续研究的设计。核心C的工作将与动物/病理核心对接，特别是 关于研究设计，因为动物研究是计划和执行的。核心C级员工拥有 支持癌症研究的丰富经验，具有坚实的基础科学、翻译学背景 除了研究和临床试验之外，他们本身也是统计方法的研究员。带着他们的众多 凭借在PDT集团多年的经验，他们期待着双方进一步的合作机会 应用现有方法，并根据需要调整或开发新方法。

Abstract Core C The goals of Core C (Biostatistics and Data Management) are to provide expert biostatistical guidance in the design, conduct and analysis of research projects comprising the program project and to assist the clinical investigators in developing a reliable and accurate data management system. Core C will provide biostatistical support to the research projects at every stage of the research. Core staff will work with investigators to develop efficient designs and sample sizes that will give adequate power to address study objectives. For clinical studies, we will contribute to the design of case report forms that collect all required information in an unambiguous way. As studies proceed, Core staff will assist in reviewing project databases and monitoring the quantity and quality of data collected, and will suggest modifications to the design or analysis plan as appropriate. Core members will conduct correct and efficient data analyses, prepare any necessary graphs and tables, assist investigators with the preparation of presentations and manuscripts, and consult on the design of subsequent research. The work of Core C will interface with the Animal/Pathology Core, particularly with respect to study design, as animal studies are planned and executed. The Core C staff members have extensive experience supporting cancer research, with strong backgrounds in basic science, translational research and clinical trials in addition to being themselves researchers in statistical methods. With their many years of experience with the PDT group, they look forward to further collaborative opportunities for both applying existing methods and adapting or developing new methods as needed.