Determinants of HPV vaccination for Hispanic parents from the Texas-Mexico border

描述(由申请者提供)：与全国相比，德克萨斯州和墨西哥边境的拉美裔女性患宫颈癌和死于宫颈癌的病例更多。宫颈癌是可以使用HPV疫苗预防的，建议11-26岁的女孩/男孩和妇女/男子接种这种疫苗。与美国拉美裔女孩相比，德克萨斯州拉美裔女孩(13-17岁)接种�1剂HPV疫苗的比例较小(65%对58%)，完成疫苗系列的较少(�3剂；42%对35%)。鉴于这一地区拉美裔妇女在宫颈癌发病率和死亡率方面的差异，促进采用疫苗并遵守其剂量计划具有重要的公共卫生意义。这项研究计划的目的是检查拉美裔母亲打算接种疫苗的决定因素，以及为她们11-17岁的女儿实际开始和完成三剂疫苗系列的情况。拟议的研究计划寻求：(1)确定母亲接种HPV疫苗的意图、开始和完成的决定因素；(2)了解提供者对推荐疫苗的观点；以及(3)为德克萨斯州-墨西哥边境的低收入拉美裔母亲设计一种与文化相关、理论上有基础的HPV干预措施。这项研究具有创新性，因为它：(1)侧重于针对服务不足的弱势群体和有特殊需求的弱势群体；(2)评估针对拉美裔母亲的以诊所为基础的宫颈癌预防干预措施的可行性；(3)侧重于父母、孩子和提供者之间的人际沟通。这些目标的实现将进一步证明父母和提供者在提高女孩的HPV疫苗接种率和完成率以消除这一人群中的宫颈癌差距方面所发挥的关键作用。

DESCRIPTION (provided by applicant): Hispanic women along the Texas-Mexico border experience more cases of and deaths from cervical cancer compared to the nation. Cervical cancer is preventable using the HPV vaccine, which is recommended for girls/boys and women/men aged 11-26. Compared to U.S. Hispanic girls, a smaller proportion of Texas Hispanic girls (ages 13-17) (65% vs. 58%) receive �1 dose HPV vaccine and fewer complete the vaccine series (�3 doses; 42% vs. 35%). Given the cervical cancer disparities in incidence and death among Hispanic women in this area, it is of great public health importance to promote the adoption of the vaccine and compliance with its dosing schedule. The objective of this research plan is to examine determinants of Hispanic mothers' intention to vaccinate and actual initiation and completion of the three dose series for their daughter aged 11-17. The proposed research plan seeks to: (1) identify determinants of mothers' HPV vaccine intentions, initiation and completion; (2) understand providers' perspectives on recommending the vaccine; and (3) design a culturally-relevant, theoretically grounded HPV intervention for low-income, Hispanics mothers along the Texas-Mexico border. The research is innovative because it: (1) focuses on a on a largely underserved, vulnerable population with specific needs; (2) assesses the feasibility of a clinic-based, cervical cancer prevention intervention for Hispanics mothers; and (3) focuses on the interpersonal communication between the parent, the child, and the provider. Achievement of the aims will contribute further evidence regarding the critical role of parents and providers in increasing HPV vaccine uptake and completion among girls to eliminate cervical cancer disparities among this population.