Mobile Media Intervention for Family Caregivers of Veterans with Dementia

描述（由申请人提供）： 这是一个应用程序的VA康复研究和发展（RR&D）小型项目在康复研究（SPiRE）奖提交的布莱克K。Scanlon博士他目前是斯坦福大学/VA老龄化临床研究中心的临床研究助理（相当于助理教授），在收到RR&D CDA-2（痴呆症护理者康复：加强退伍军人和以家庭为中心的护理，1 IK 2 RX 001240 - 01 A1; JIT过程完成，开始日期待定）后，他将接受8/8次VA预约。斯坎伦博士正在确立自己作为一个临床科学家谁进行以病人和家庭为中心的痴呆症和神经退行性疾病的临床研究。该奖项将为Scanlon博士及其团队提供开发新项目所需的资源，该项目旨在通过利用移动的媒体设备（即，平板电脑），以服务于其他家庭照顾者的退伍军人与痴呆症在舒适的自己的家。为了实现这一目标，他组建了一个包括三名合作研究者的团队：杰罗姆耶萨维奇博士（老年精神病学家，认知和精神功能方面的知名专家）;乔伊·泰勒博士（认知心理学家和认知衰退轨迹专家）;还有丽莎木下医生（临床神经心理学家，在痴呆症认知和行为症状的评估和治疗方面具有专业知识）;高级研究员：玛丽Mittelman博士（国际知名的痴呆症护理干预专家）和顾问：Booil Jo博士（生物统计学家，擅长临床试验设计/分析、纵向数据分析和缺失数据分析）。拟议的项目研究教育和技能建设康复（ESBR）干预的影响，旨在使用移动的媒体设备的低成本和临床可扩展性，对老年痴呆症退伍军人的家庭照顾者。共有40名照顾痴呆退伍军人的护理人员将被随机分配至移动的媒体ESBR干预组（ESBR-m; n=20）或常规护理加纸质教育材料组（UC; n=20）。干预效果将在干预后三个月进行检查。本研究的主要目的是确定通过移动的媒体设备（例如，平板电脑，如iPad）。Scanlon博士还将使用先进的统计技术（例如，混合效应模型），以评估干预对以下方面的影响：生活质量（具体目标1）;感知压力和抑郁症状（具体目标2）;以及痴呆退伍军人照顾者的社会化和愉快活动参与（具体目标3）。该奖项将创造一个理想的环境，Scanlon博士和他的团队可以建立必要的试点数据，以开拓低成本，实用和临床可翻译的方法的发展，以改善VHA内神经退行性疾病和痴呆症的康复和管理。

DESCRIPTION (provided by applicant): This is an application for a VA Rehabilitation Research and Development (RR&D) Small Projects in Rehabilitation Research (SPiRE) Award submitted by Blake K. Scanlon, Ph.D. He is currently a Clinical Research Associate (Assistant Professor equivalent) at the Stanford/VA Aging Clinical Research Center with a pending 8/8ths VA appointment subsequent to receipt of a RR&D CDA-2 (Dementia caregiver rehabilitation: enhancing Veteran and family-centered care, 1 IK2 RX001240-01A1; JIT process complete, start date pending). Dr. Scanlon is establishing himself as a clinician-scientist who conducts patient- and family-centered clinical research on dementia and neurodegenerative disease. This award will provide Dr. Scanlon and his team with the resources necessary to develop a novel project aiming to expand the reach of the CDA-2 intervention study by utilizing mobile media devices (i.e., tablets) to serve additional family caregivers of Veterans with dementia in the comfort of their own homes. To accomplish this goal, he has gathered a team that includes three Co-Investigators: Dr. Jerome Yesavage (a geriatric psychiatrist and renowned expert in cognitive and psychiatric functioning across the lifespan); Dr. Joy Taylor (a cognitive psychologist and expert in the trajectory of cognitive decline); and Dr. Lisa Kinoshita (a clinical neuropsychologist with expertise in the assessment and treatment of cognitive and behavioral symptoms in dementia); a Senior Researcher: Dr. Mary Mittelman (an internationally renowned expert in dementia caregiver intervention) and a consultant: Dr. Booil Jo (a biostatistician with expertise in design/analysis of clinical trials, longitudinal data analysis, and missing data analysis). The proposed project studies the effects of an education and skill-building rehabilitation (ESBR) intervention, designed to be low-cost and clinically scalable using mobile media devices, on family caregivers of Veterans with dementia. A total of 40 caregivers caring for a Veteran with dementia will be randomized to mobile media ESBR intervention (ESBR-m; n=20) or to usual care plus paper educational materials (UC; n=20). Intervention effects will be examined at three months post-intervention. The Primary Aim of this study is to establish the feasibility of delivering a group-based intervention to family caregivers of Veterans through mobile media devices (e.g., tablets such as the iPad). Dr. Scanlon will also use advanced statistical techniques (e.g., mixed-effects modeling) to evaluate the impact of the intervention on: quality of life (Specific Aim 1); perceive stress and depressive symptoms (Specific Aim 2); and socialization and engagement in pleasant activities (Specific Aim 3) in caregivers of Veterans with dementia. This award will create an ideal environment where Dr. Scanlon and his team can establish the necessary pilot data to pioneer the development of low-cost, pragmatic and clinically translatable methods for improving rehabilitation and management of neurodegenerative disease and dementia within VHA.