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中文摘要
翻译
行政核心的总体目标是作为DTSGC的综合单位, 密切协调其他核心的功能:数据生成核心(DGC),数据分析和 Signature Development Core(SGC)和Community Interactions and Outreach Core(CIO)。一个复杂 像DTSGC这样的项目需要灵活和主动的管理方法, 科学的做法与良好的管理原则,以简化工作流程。行政核心将 有适当的机制来处理新的和有时意想不到的挑战, 以持续的方式高效。工作流程的效率将与质量保证密切相关, 质量控制,以及对质量和遵守SOP的持续承诺将渗透到 DTSGC。启用QA/QC将是CAC的中心重点。管理核心将确保数据 并且签名生成与数据发布和社区交互很好地集成。这种集成 需要不断地培养和管理。CAC将提供行政支持, 副理事会和秘书长理事会的产出顺利地流向首席信息干事核心,以便分发。很可能会有意想不到的 随着项目的进行,科学和程序都面临挑战。通过不断监测和分析 CAC将识别数据中的薄弱点,并使用流程工程协议进行签名 发电供应链,使协议的变化,以考虑到意外的科学问题,f 技术进步提高了流程效率和中途修正。整体 行政核心将发挥粘合剂的作用,将DTSGC的所有部分粘合在一起。
英文摘要
The overall goal of the Administrative Core is to function as the integrative unit of the DTSGC to enable the close coordination of the functions of the other Cores: Data Generation Core (DGC), the Data Analysis & Signature Development Core (SGC) and the Community Interactions and Outreach Core (CIO). A complex project such as the DTSGC requires nimble and proactive management approaches that merge good scientific practices with good management principles to streamline workflow. The Administrative Core will have mechanisms in place to deal with new and sometime unanticipated challenges so that workflow is efficient in an ongoing manner. Efficiency in workflow will be to be closely coupled to quality assurance and quality control, and a constant commitment to quality and adherence to SOPs will permeate all facets of the DTSGC. Enabling QA/QC will be a central focus of the CAC. The Administrative Core will ensure that Data and signature generation is well-integrated with data release and community interactions. This integration needs to be continually nurtured and managed. The CAC will provide the administrative support to enable smooth flow of DGC and SGC outputs to CIO core for dissemination. There are likely to be unanticipated challenges both scientific and procedural as the project proceeds. Through ongoing monitoring and analyses and use of process engineering protocols the CAC will identify weak points in the data to signature generation supply chain to enable change in protocols to account for unanticipated scientific issues, f increase in process efficiency and mid-course corrections resulting from advances in technologies. Overall the Administrative Core will function as the glue that holds all parts of the DTSGC together.
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Gelbrane: Combined Gel and Membrane for Robust Western Blotting
  • 批准号:
    10759072
  • 项目类别:
  • 资助金额:
    $29.77万
  • 财政年份:
    2023
  • 负责人:
    Marc R. Birtwistle
  • 依托单位:
Accessible and Robust High-Throughput Western Blotting for Small Sample Sizes
  • 批准号:
    10545990
  • 项目类别:
  • 资助金额:
    $28.88万
  • 财政年份:
    2022
  • 负责人:
    Marc R. Birtwistle
  • 依托单位:
Mechanistic Pharmacodynamic Modeling for Drug Combination Responses
  • 批准号:
    10398952
  • 项目类别:
  • 资助金额:
    $37.23万
  • 财政年份:
    2021
  • 负责人:
    Marc R. Birtwistle
  • 依托单位:
Mechanistic Pharmacodynamic Modeling for Drug Combination Responses
  • 批准号:
    10580895
  • 项目类别:
  • 资助金额:
    $25.0万
  • 财政年份:
    2021
  • 负责人:
    Marc R. Birtwistle
  • 依托单位:
海外基金