Midwest Roybal Center for Health Promotion and Translation

总体摘要 我们提议的UIC中西部Roybal健康促进和翻译中心旨在加速 将行为研究理论转化为实际成果，以改善功能和生活质量 的老年人。我们的工作认识到，针对个人的干预措施发生在家庭中， 社区和社区受到影响启动和 保持行为改变。我们的工作以RE-AIM框架为指导， 最有可能产生广泛公共卫生影响的干预措施。我们的中心将支持 设计和测试以原则为导向的、有效的健康促进干预措施，这些措施有很强的承诺， 通过NIH阶段变化模型。我们建议的更新中心保留其目前的重点， 为老年种族/少数民族成年人设计干预措施，并扩大我们健康行为的重点 干预措施包括认知健康。此更新应用程序针对四个重点主题领域：物理 活动促进;增强活动性，广义定义包括改善认知功能步态，平衡， 和步行;利用技术来提高干预的可扩展性和保真度;并将 维持行为改变的行动机制。 我们的管理团队、受资助试点项目的高级领导人和首席研究员将构成 中心研究员。管理团队和高级领导人具有开展研究的经验 在阶段模型的所有阶段，并将努力尽快过渡有前途的飞行员跨越阶段， 可能试点项目参与者将负责完成其项目中建议的所有活动， 管理核心的监督。试点核心将为每年最多两个试点项目提供赠款， 从UIC和伊利诺伊大学其他校区的所有部门征求。续贷中心 执行委员会由UIC多个部门的高级领导和主席组成，所有这些部门都 对完成中心的使命至关重要。该中心的整体业绩将以 杰出的咨询委员会，包括来自不同的学术代表，供应商，资助者， 消费者和媒体利益相关者群体。最后，这一更新申请首次纳入了 多模式ADRD成像和连接组学核心，使研究者能够进行脑成像， 解释和存储，并提供对统一的认知和身体活动测量的访问。

Abstract Overall Our proposed UIC Midwest Roybal Center for Health Promotion and Translation seeks to accelerate the translation of behavioral research theories into practical outcomes to improve the functioning and quality of life of older adults. Our work recognizes that interventions that target individuals take place in families, neighborhoods, and communities that are impacted by external factors that influence initiation and maintenance of behavior change. Our work is guided by the RE-AIM Framework to identify health promotion interventions that have the greatest potential for broad based public health impact. Our Center will support the design and testing of principle-driven, potent health promotion interventions that have strong promise of progressing through the NIH Stage Change Model. Our proposed renewal Center retains its current focus on designing interventions for older racial/ethnic minority adults and expands the focus of our health behavior interventions to include cognitive health. This renewal application targets four thematic areas of focus: physical activity promotion; enhancing mobility, defined broadly to include improved cognitive function gait, balance, and walking; harnessing technology to improve intervention scalability and fidelity; and incorporating mechanisms of action that will sustain behavior change. Our Management team, Senior Leaders and Principal Investigators of funded pilot projects will constitute the Center Research Faculty. The Management team and Senior Leaders have experience conducting research across all stages of the Stage Model and will work to transition promising pilots across the Stages as quickly as possible. The Pilot PIs will be responsible for completing all activities proposed in their projects, under the oversight of the Management Core. The Pilot Core will provide grant funding for up to two pilots per year, solicited from all departments across UIC and other University of Illinois campuses. The renewal Center Executive Committee is comprised of Senior Leaders and Chairs of multiple departments at UIC, all of which are critical to fulfilling the mission of the Center. The overall performance of the Center will be guided by a distinguished Advisory Committee that includes representatives from diverse academic, provider, funder, consumer, and media stakeholder groups. Finally, this renewal application incorporates for the first time a Multi-modal ADRD Imaging and Connectomics Core that will enable investigators to perform brain imaging, interpretation, and storage and provide access to uniform cognitive and physical activity measures.