Synthesis of Therapeutic Agents for Treatment of Infectious Diseases

国家过敏和传染病研究所（NIAID），国家卫生研究院（NIH），卫生和人类服务部（DHHS）支持与微生物学和免疫学的基本理解相关的研究，从而开发疫苗，疗法和医学诊断，用于预防，治疗和诊断传染病和免疫介导的疾病。国家艾滋病研究所艾滋病司要求合成针对艾滋病毒和其他传染病的治疗药物以及用于治疗和抗艾滋病毒的局部杀微生物剂。这一举措为合成杀微生物剂和化合物提供了资源，用于治疗艾滋病毒和与国家艾滋病研究所研究议程相关的其他传染病。如果有必要，该合同将按照FDA现行的良好生产规范（cGMP）规定合成化学品，数量需要用于体外筛选、动物或早期I期临床研究。

The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. The NIAID Division of AIDS has a requirement for the synthesis of therapeutics directed against HIV and other infectious diseases as well as agents to serve and anti-HIV topical microbicides. This initiative provides the resources for the synthesis of microbicides and compounds for the treatment of HIV, and other infectious diseases of relevance to the research agenda of NIAID. The contract will synthesize chemicals, in compliance with FDA’s current Good Manufacturing Practice (cGMP) regulations if necessary, in quantities needed for testing in in vitro screens, animals, or early Phase I clinical studies.