Arkansas ECHO ISPCTN Site (AREIS)

项目摘要 生活在美国农村地区的儿童参与研究的机会有限。的 机构发展奖（IDEA）计划于1993年推出，以加强生物医学研究 在国家卫生研究院资助率低的州提供机会。环境对 儿童健康结果（ECHO）IDEA国家儿科临床试验网络（ISPCTN）成立于2015年， 为居住在IDEA州的儿童提供参与临床试验的机会，并提高劳动力的能力 用于儿科临床试验位于阿肯色州儿童研究中心的ARCHEECHO ISPCTN网站（AREIS） 研究所将在以往工作的基础上继续扩大儿童参与研究的机会 生活在阿肯色州的农村地区。为此，AREIS将继续与数据协调中心密切合作， 和运营中心，与其他ISPCTN网站，并与当地专家附属于临床和 阿肯色州大学医学科学转化科学奖。在下一轮融资中， AREIS将1）为ECHO ISPCTN提供研究专业知识和领导， 在高优先级ECHO重点领域实施稳健的临床试验; 2）提高临床试验能力 和领导技能之间的AREIS教师和工作人员;和3）利用现有资源，以实施创新 社区参与和社区伙伴关系办法，以加强农村妇女的参与， 临床试验中的儿童临床试验中的创新，如采用远程保健方法，将 允许AREIS在资源匮乏的环境中进行研究，如农村社区。的集体影响 这项研究随着ECHO重点地区临床试验中农村儿童入组人数的增加， 临床试验能力的教师和工作人员与AREIS附属。此外，持续发展 与其他ISPCTN站点和DCOC建立强有力的合作伙伴关系将促进未来研究的成功 欧盟人道处优先领域的合作。

PROJECT SUMMARY Children living in rural regions of the United States have limited opportunities for research participation. The Institutional Development Award (IDeA) Program was launched in 1993 to enhance biomedical research opportunities in states with low rates of National Institutes of Health funding. The Environmental influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN) was formed in 2015 to provide clinical trial participation opportunities to children living in IDeA states and to enhance workforce capacity for pediatric clinical trials. The ARkansas ECHO ISPCTN Site (AREIS) based at Arkansas Children’s Research Institute will build upon previous work and continue to expand research participation opportunities for children living in rural regions in Arkansas. To this end, AREIS will continue to work closely with the Data Coordinating and Operations Center, with other ISPCTN sites, and with local experts affiliated with the Clinical and Translational Sciences Award at the University of Arkansas for Medical Sciences. In the next cycle of funding, AREIS will 1) provide research expertise and leadership to the ECHO ISPCTN for the development and implementation of robust clinical trials in high priority ECHO focus areas; 2) increase clinical trials competency and leadership skills among AREIS faculty and staff; and 3) leverage existing resources to implement innovative community engagement and community partnership approaches that will enhance the participation of rural children in clinical trials. Innovations in clinical trials, such as the incorporation of telehealth approaches, will allow AREIS to conduct research in low-resourced settings, such as rural communities. The collective impact of this research with increase the enrollment of rural children in clinical trials in ECHO focus areas and increase clinical trial competencies among faculty and staff affiliated with AREIS. In addition, the continued development of strong partnerships with other ISPCTN sites and the DCOC will enhance the success of future research collaborations in ECHO priority areas.