Surveillance of Diabetes in Young Adults between 18-45 Years of Age (DiCAYA) - Component B

项目总结 糖尿病患者发生一系列不同的微血管、大血管和 与高发病率相关的神经性并发症，并侵蚀他们的生活质量。糖尿病是 预计将在美国(美国)造成越来越大的财务损失未来，特别是在 处于工作年龄的成年人。持续、及时和有效地监测确诊的1型和2型糖尿病 在18-45岁的年轻人中发现健康差距并向卫生保健系统提供信息是至关重要的 以及公共卫生界，以确定预防糖尿病及其并发症的战略并确定优先事项。 科罗拉多州迪卡亚监视团队是解决利用现有 电子数据来源，以生成准确、及时的糖尿病发病率和患病率估计 在按类型、年龄、性别和种族/族裔分组的青壮年人口中。为回应RFA-DP-20- 001-B部分，我们建议确定以下人群中糖尿病的年患病率和发病率 从2020年开始，科罗拉多州18-45岁的成年人来自以下数据 资料来源：1)来自内分泌诊所搜索网络的电子健康记录， 科罗拉多州的社区诊所和医院网络；2)全州范围内的立法授权所有付款人索赔 包含超过33个商业健康计划和100%的医疗补助申请的数据库；以及3) 科罗拉多州卫生系统数据仓库(Health Data Compass)。我们简单但创新的集成 监视方法将利用算法、增量记录链接和目标图表的组合 回顾以确定青壮年糖尿病患者，区分糖尿病类型和估计诊断日期。我们的 具体目标是：目标1：监测(流行率)--确定#年流行的糖尿病病例 18-45岁的年轻人，按年龄、种族/族裔和糖尿病类型分列；目标2：监测 (发病率)-在确诊时年龄在18-45岁的年轻人中确定新诊断的糖尿病病例，通过 年龄、种族和糖尿病类型；目标3：评估公共卫生监测方法--至 评估我们的综合监测方法的优势和挑战，以确定负担和 18-45岁青年糖尿病发病率通过确定有效性、完整性和 案例查明方法的代表性。

PROJECT SUMMARY People with diabetes are at high risk of developing a range of diverse microvascular, macrovascular and neuropathic complications that are associated with high morbidity and erode their quality of life. Diabetes is expected to take an increasingly large financial toll in in the United States (U.S.) the future, particularly among working age adults. Ongoing, timely and efficient surveillance of type 1 and type 2 diabetes diagnosed among young adults aged 18-45 years is essential to identify health disparities and inform health care systems and the public health community to identify and prioritize strategies to prevent diabetes and its complications. The Colorado DiCAYA surveillance team is ideally situated to address the critical challenge of utilizing existing electronic data sources to generate accurate, timely estimates of the incidence and prevalence of diabetes among the young adult population by type, age, sex, and race/ethnicity subgroups. In response to RFA-DP-20- 001- Component B, we propose to ascertain the annual prevalence and incidence of diabetes among adults aged 18-45 years of age in the state of Colorado starting with year 2020 from the following data sources: 1) electronic health records from the well-established SEARCH network of endocrinology clinics, community clinics and hospital networks in Colorado; 2) a state-wide, legislatively mandated All Payers Claims Database that contains over 33 commercial health plans and 100% of Medicaid claims; and 3) the University of Colorado Health System data warehouse (Health Data Compass). Our simple, yet innovative integrated surveillance approach will utilize a combination of algorithms, incremental record linkage and targeted chart review to identify young adults with diabetes, distinguish diabetes type and estimate date of diagnosis. Our specific aims are: Aim 1: SURVEILLANCE (Prevalence)- To ascertain cases of prevalent diabetes among young adults age 18-45 years, by age, race/ethnicity and diabetes type; Aim 2: SURVEILLANCE (Incidence)- To ascertain newly diagnosed diabetes cases in young adults age 18-45 years at diagnosis, by age, race and diabetes type; Aim 3: EVALUATE PUBLIC HEALTH SURVEILLANCE METHODS - To evaluate the strengths and challenges of our integrated surveillance approach to determine the burden and incidence of diabetes among young adults 18-45 years by ascertaining validity, completeness and representativeness of case ascertainment methods.