Interdisciplinary Training in Rheumatic Diseases

项目总结 此续约申请寻求对风湿性T-32跨学科训练的持续支持 范德比尔特大学的疾病。该计划寻求对2个博士后和3个博士后职位的支持。 该计划的目标是为下一代调查人员提供必要的工具，以使 关键发现，并促进我们对复杂风湿性疾病的理解和治疗。我们的 教师们创造了一个互动的发现环境，将临床研究和基础研究联系起来 博士后和博士后实习生。跨学科的方法与精心策划的指导相结合。 过程，以便为学员提供广阔的视角，并使他们接触到 对单个实验室无法解决的问题进行临床翻译。该计划中的教官是 高度互动，并在研究小组之间保持广泛的合作努力。这些 互动在项目中创建了四个兴趣小组：先天免疫和获得性免疫；血管生物学 和炎症；精密医学；和肌肉骨骼生物学。该计划的组织是为了满足 希望将先进技术(如基因组学或蛋白质组学)应用于 风湿病以及支持那些想要将这些进步转化为 改善医疗保健。除了部门和讲师特定实验室指导外，每个受训人员 通过跨学科课程接受风湿病研究培训。联合研究 论坛、期刊俱乐部和共享的核心设施促进了超越单个实验室或部门的互动。 该项目的实习生由教职员工积极指导，并由 以前的学生和项目中的高级研究员。MSCI和公共卫生硕士的学位授予途径将是 可供该计划使用。对该司设施的重大机构投资和招聘 优秀的新教师进一步加强了未来的计划。

PROJECT SUMMARY This renewal application seeks continued support for the T-32, Interdisciplinary Training in Rheumatic Diseases at Vanderbilt University. The program seeks support for 2 predoctoral and 3 postdoctoral positions. The goal of the program is to provide the next generation of investigators with the tools necessary to make critical discoveries and to advance our understanding and treatment of complex rheumatic disorders. Our faculty have created an interactive environment of discovery that bridges both clinical and basic research for pre and post-doctoral trainees. An interdisciplinary approach is coupled with a carefully orchestrated mentoring process so that trainees are provided with a broad perspective and they are exposed to opportunities for clinical translation of problems that cannot be solved by a single laboratory. The preceptors in the program are highly interactive and maintain extensive collaborative efforts between and among the research groups. These interactions create four Interest Groups within the program: Innate and Adaptive Immunity; Vascular Biology and Inflammation; Precision Medicine; and Musculoskeletal Biology. The program is organized to meet the career goals of individuals who want to apply advanced technologies, such as genomics or proteomics to rheumatic disease as well as to support the careers of individuals who want to translate these advances to improve health care. In addition to Departmental and preceptor-specific laboratory instruction, each trainee receives rheumatic disease research training through an interdisciplinary curriculum. Combined research forums, journal clubs and shared core facilities promote interactions beyond individual laboratories or divisions. Trainees in the program are actively mentored by both faculty members and through “peer mentoring” by former students and senior fellows in the program. Degree granting pathways for MSCI and MPH will be available to the program. Significant institutional investment in the Division's facilities and the recruitment of outstanding new faculty further strengthen the program for the future.