Viral Oncology Training Grant

项目摘要/摘要 要求继续支持杜克大学医学院的病毒肿瘤学培训方案 中心。该计划自1975年以来一直得到资助，这是要求延长该计划第七个任期的请求 程序。请拨经费支持3名博士前实习生和5名博士后实习生。这个 参与的教职员工由杜克大学医学中心的21名成员组成，其中许多人拥有初级或 分子遗传学和微生物学系的二次任命。其他参赛者 教职员工在内科、儿科、神经外科、外科、药理学等系有聘任 和癌症生物学，或人口健康科学。参与研究的教职员工范围 从病毒复制和病毒/宿主相互作用的基础分子遗传学研究，到病毒和 人类免疫缺陷病毒的细胞癌基因作用、免疫学和分子病毒学 致癌病毒和病毒在人类恶性肿瘤治疗方法中的使用。这个 研究计划已被证明是博士后和博士后实习生的有效培训基础。 博士前课程包括四个学期的学术工作，然后是初步考试。vt.在.的基础上 成功完成这些要求后，全职研究将占据培训计划的其余部分。 博士后培训计划的重点是参与实验室的全日制研究。这两个 博士后和博士后计划通过各种不同的系级和计划研讨会系列来加强 类型以及病毒学期刊俱乐部，每月为参与的实验室和 一年一度的两次小型研讨会，一次在秋季举行，主题是“病毒肿瘤学和艾滋病恶性”，另一次在春季举行 “人类致病病毒”。这些活动促进了项目成员之间的交流，并与 杜克大学的其他学生和教职员工，不仅对受训人员，而且对整个机构都有最终的好处。 学员还获得了丰富的职业和职业发展培训和机会。 这些培训包括拨款撰写、科学陈述、由敬业的教师提供职业指导和建议。 委员会和外部咨询委员会，并与VOTG校友网络整合，目前已有200多人 在生物医学研究企业的版图中表现强劲。

PROJECT SUMMARY/ABSTRACT Continued support is requested for a training program in Viral Oncology at Duke University Medical Center. The program has been funded since 1975 and this is a request for renewal for the seventh term of the program. Funds are requested for the support of 3 predoctoral trainees and 5 postdoctoral trainees. The participating faculty consists of 21 members of Duke University Medical Center, many of whom have primary or secondary appointments in the Department of Molecular Genetics and Microbiology. The additional participating faculty have appointments in the Departments of Medicine, Pediatrics, Neurosurgery, Surgery, Pharmacology and Cancer Biology, or Population Health Sciences. The research interests of the participating faculty range from basic molecular genetic studies of virus replication and virus/host interactions, to the study of viral and cellular oncogene action, the immunology and molecular virology of the human immunodeficiency virus as a cancer-predisposing virus and the use of viruses in approaches to the treatment of human malignancies. The research program has proven to be an effective training basis for both predoctoral and postdoctoral trainees. The predoctoral program involves four semesters of academic work followed by a preliminary examination. Upon successful completion of these requirements, full time research occupies the remainder of the training program. The postdoctoral training program is focused on full time research in the participating laboratories. Both the predoctoral and the postdoctoral program are enhanced by departmental and program seminar series of various types as well as a virology journal club, monthly works in progress meetings for participating laboratories and two annual minisymposia, one in the fall on “Viral Oncology and AIDS Malignancy” and one in the spring on “Pathogenic Human Viruses." These activities foster communication between members of the program, and with other students and faculty at Duke, to the ultimate benefit of not only the trainees but the institution in general. Trainees are also provided with a wealth of career and professional development training and opportunities. These include training in grant writing, scientific presentation, career mentoring by dedicated faculty advising committees and an external advisory committee, and integration with a network of VOTG alumni now over 200 strong across the landscape of the biomedical research enterprise.