Mays Cancer Center at UT Health SA

项目概要-光学成像共享资源 光学成像共享资源（OISR）的使命是提供最先进的光学成像 Mays癌症中心（MCC）和德克萨斯大学健康圣安东尼奥的成员 (UT Health SA）。OISR自1999年以来一直在运作，当时它首次被列为癌症中心- 支持共享资源。OISR共有2，400平方米。英尺位于校园两个地点的空间， 1，000平方英尺在主校区的牙科学校大楼和一个1,400平方英尺的设施。德克萨斯州南部的一个设施 研究设施建设（STRF）在Greehey校园。这座最先进的设施由以下机构共同管理： 癌症中心和UT Health SA。OISR拥有广泛的现代光学成像系统 为了满足癌症研究所需的各种生物医学体外和体内应用的需求， 从单个分子到整个动物，从培养的细胞到深层组织，包括高时间分辨率， 快速事件的活细胞成像。我们的系统包括共焦/多光子显微镜、宽视野显微镜， 荧光寿命成像显微镜，荧光光谱成像，超分辨，光片 显微镜和整体动物成像。服务包括一对一、动手培训和协助 仪器操作和图像分析，获得最先进的光学成像仪器，咨询 实验设计和样品制备，以及资助申请的支持信。内工作人员 OISR包括：James Lechleiter博士（董事），王爱星博士导演：Jimmy Wewer （图像技术员）。在最近的获奖年度，OISR被21个癌症中心成员使用， 同行评审资金，占共享资源用户总数的27%。

Project Summary—Optical Imaging Shared Resource The mission of the Optical Imaging Shared Resource (OISR) is to provide state-of-the-art optical imaging methodologies to members of the Mays Cancer Center (MCC) and the University of Texas Health San Antonio (UT Health SA). The OISR has been in operation since 1999, when it was first included as a Cancer Center- supported Shared Resource. The OISR has a total of 2,400 sq. ft. of space located in two sites on campus, a 1,000 sq.ft. facility in the Dental School building on the main campus and a 1,400 sq.ft. facility in the South Texas Research Facility Building (STRF) on the Greehey Campus. This state-of-the-art facility is managed jointly with the Cancer Center and the UT Health SA. The OISR houses a wide spectrum of modern optical imaging systems to meet the demands for various biomedical in vitro and in vivo applications needed for cancer research, from single molecules to whole animals and from cultured cells to deep tissue, including high temporal resolution for live cell imaging of rapid events. Our systems include confocal/multiphoton microscopy, widefield microscopy, fluorescence lifetime imaging microscopy, fluorescence spectral imaging, super resolution, light sheet microscopy, and whole animal imaging. Services include one-on-one, hands-on training and assistance with instrument operation and image analysis, access to state-of-the-art optical imaging instrumentation, consultation on experimental design and sample preparation, and supporting letters for grant applications. The staff in the OISR include: James Lechleiter, Ph.D. (Director), Exing Wang, Ph.D. (Co-Director), and Jimmy Wewer (Imaging Technologist). In the most recent award year, the OISR was used by 21 Cancer Center members with peer-reviewed funding, which comprises 27% of the total Shared Resource users.