Developmental Core

发展核心：抽象 上游研究中心的发展核心将促进创新和协作 与癌症预防和控制对持续贫困社区的影响有关的研究。这个 CORE将通过激励新的研究方向，在推进中心的使命方面发挥关键作用 癌症的上游根本原因，促进跨中心活动的跨学科合作。 发展核心将利用研究专业知识的广度和深度 北加州三个综合性癌症中心的贫困和癌症：斯坦福大学 加州大学旧金山分校(UCSF)和加州大学戴维斯分校(UCD)。获得资助的项目将 协同并推广在项目1和项目2下进行的研究，以及研究和方法 核心。我们建议在三个相辅相成的研究轨道上资助试点项目：1)支持 与收入支持和癌症公平相关的社区优先干预措施和项目，2)阐明 将缺乏收入与癌症不平等的驱动因素联系起来的机制，以及3)促进合作 早期职业学者、临床医生和社区合作伙伴之间的跨学科项目。资金将是 由调查人员和社区合作伙伴用来开发试点数据，作为获得 通过外部同行评审赠款为后续研究提供资金。我们将与我们的 社区合作伙伴、持久贫穷倡议网络和网络指导委员会。目标1 核心是每年管理和支持3个试点项目，以促进创新和合作研究 与GBI和EITC计划对我们选定社区的癌症预防和控制的影响有关 以及持续的贫困。核心目标2是建设可持续双向伙伴关系的能力 大学和社区合作伙伴之间通过以下方式减少持续贫困地区的癌症不平等 社区驱动的研究。发展的核心活动的可持续产品将是创造 合作研究持续贫困中癌症的社会决定因素的新途径 社区、对中心活动的广泛跨学科参与以及飞行员的职业发展 项目获奖者致力于对加利福尼亚州北部持续贫困地区的研究。

DEVELOPMENTAL CORE: ABSTRACT The Developmental Core of the UPSTREAM Research Center will foster innovative and collaborative research related to the impact of cancer prevention and control in communities with persistent poverty. The Core will play a key role in advancing the mission of the Center by stimulating novel research directions toward the upstream fundamental causes of cancer, facilitating transdisciplinary collaboration across Center activities. The Developmental Core will capitalize on the breadth and depth of research expertise at the intersection of poverty and cancer at the three Comprehensive Cancer Centers in Northern California: Stanford, the University of California at San Francisco (UCSF), and the University of California at Davis (UCD). Funded projects will synergize with, and extend the research performed under Projects 1 and 2, and the Research and Methods Core. We propose to fund pilot projects in three complementary research tracks: 1) Supporting community prioritized interventions and projects related to income support and cancer equity, 2) Elucidating mechanisms linking lack of income to drivers of cancer inequities, and 3) Facilitating collaborative transdisciplinary projects between early career scholars, clinicians, and community partners. Funds will be used by investigators and community partners to develop pilot data that will serve as the basis for obtaining subsequent research funding through external peer-reviewed grants. We will work collaboratively with our community partners, the Persistent Poverty Initiative Network, and the Network Steering Committee. Aim 1 of the Core is to administer and support 3 pilot projects per year to catalyze innovative and collaborative research related to the impact of GBI and EITC programs on cancer prevention and control in our selected communities with persistent poverty. Aim 2 of the Core is to build capacity for sustainable bi-directional partnerships between university and community partners to reduce cancer inequalities in persistent poverty areas through community-driven research. The sustainable products of the Developmental Core activities will be the creation of novel avenues for collaborative research on the social determinants of cancer in persistent poverty communities, broad transdisciplinary participation in Center activities, and the career development of pilot project awardees committed to a focus on research in persistent poverty areas of Northern California.