Administrative and Statistics Core

行政和统计核心A摘要 行政和统计核心（行政和统计核心）提供领导、监督和 研究计划的行政支持，以及生物统计支持和监督。特别是 提供行政和财务管理、文书支持、稿件提交、会议组织， 数据管理，质量控制，计划和评估的赠款，离开研究调查员 自由地专注于科学它有两个具体目标，一个侧重于科学和业务监督， 它包括一个内部咨询委员会（IAB）和来自特设外部专家顾问（EEC）的帮助。的 第二个目标是对赠款总额进行行政和财政监督。这一目标包括： 与NCI项目官员和其他工作人员沟通和协商，进度报告和跟踪 共享资源使用。核心服务的关键是核心的生物统计支持， 包括：1）实验室和临床研究的生物统计学设计，包括样本的前瞻性设计 所有三个项目中提出的小鼠研究的大小计算和样本临床试验的设计， 项目1和3中拟定的临床研究中的样本分析; 2）研究的统计监测， 确保结果的可解释性; 3）对多名研究者进行监督和分析协助， 研究方案数据输入/统计分析和分析软件; 4）开发生物统计学 5）协助编写论文。

ADMINISTRATIVE AND STATISTICS CORE A ABSTRACT The Administrative and Statistics Core (Admin and Stats Core) provides leadership, oversight and administrative support for the research programs, as well as biostatistical support and oversight. In particular, it provides administrative and fiscal management, clerical support, manuscript submission, meeting organization, data management, quality control, and planning and evaluation of the grant, leaving the research investigators free to concentrate on science. It has two specific aims, one focused on scientific and operational oversight, which includes an Internal Advisory Board (IAB) and help from ad hoc External Expert Consultants (EEC). The second aim provides administrative and fiscal oversight to the overall grant. Within this aim is included the communication and consultation with the NCI program officer and other staff, progress reports and tracking shared resource use. The key importance to the Core's services is the Core's biostatistical support, which includes: 1) biostatistical design of laboratory and clinical studies, including prospective design of the sample size calculations for murine studies proposed in all three Projects and design of sample clinical trial and sample analyses in the clinical studies proposed in Projects 1 and 3; 2) statistical monitoring of studies to ensure interpretability of results; 3) supervision and analytical assistance to multiple investigators regarding study protocol data entry/statistical analyses and analysis software; 4) development of biostatistical methodology for statistical problems in these projects; and 5) assistance with manuscript preparation.