Duke PRIME Cancer Research Program

摘要 美国正面临着生物医学劳动力危机，首先是STEM专业的减员。 本科教育。其结果是缺乏创新的解决方案来促进健康成果。癌 仍然是发病率和死亡率的一个重要原因。癌症诊断和幸存者的患病率 美国在2020年超过1900万，全球有990万人死于癌症。杜克大学 通过建立一个强大的未来学术管道， 癌症研究者杜克癌症研究所（DCI）的研究项目在全国范围内得到认可， 癌症生物学领域;癌症预防和控制;癌症风险检测和拦截;免疫- 肿瘤学;神经肿瘤学;精确癌症医学和研究治疗学;放射肿瘤学 和成像。我们最近成立的医生科学家发展办公室（OPSD）提供了一个可持续的 指导、专业发展和研究资金的结构。通过利用这些机构 结构，我们有能力支持项目的开发、实施和评估 将整个培训范围内的资源联系起来，向本科生介绍各种癌症， 研究职业机会。为了解决癌症研究人员的缺口，我们建议杜克 准备研究学者在生物医学科学（PRIME）：癌症研究计划， 将招收本科生，并为他们提供研究技能建设， 在癌症研究方面的指导研究经验。我们将提供基于证据的专业 通过虚拟平台和项目机会开展开发活动和持续参与 校友们以点对点导师的角色回归。杜克总理：癌症研究计划将实现 我们的长期目标，解决限制癌症研究人员招聘和保留的障碍 通过早期接触密集的研究经验，创新的教学法课程，和同行 联网该计划的重点是1）提供指导夏季研究密集的经验， 2）提供一个平行的OPSD PRIME学院丰富课程，以提高 了解FDQFHU的研究概念和研究的职业道路;以及3）发展同行网络 在整个学年持续参与的模式。成功实施 拟议的计划将导致一个可扩展的模型，为不同的 跨学科的生物医学研究队伍。

ABSTRACT The U.S. is facing a biomedical workforce crisis, starting with attrition from STEM majors in undergraduate training. The result is a lack of innovative solutions to advance health outcomes. Cancer remains a significant cause of morbidity and mortality. The prevalence of cancer diagnoses and survivors in the U.S. was more than 19 million in 2020, with 9.9 million cancer-related deaths worldwide. Duke University is uniquely positioned to address this critical problem by building a robust pipeline of future academic cancer researchers. The Duke Cancer Institute (DCI) is nationally recognized for its research programs in the areas of cancer biology; cancer prevention and control; cancer risk detection and interception; immune- oncology; neuro-oncology; precision cancer medicine and investigational therapeutics; and radiation oncology and imaging. Our recently established Office of Physician Scientist Development (OPSD) offers a sustainable structure for mentorship, professional development, and research funding. By leveraging these institutional structures, we are well positioned to support the development, implementation, and evaluation of a program that links resources across the training spectrum to introduce undergraduate students to varied cancer research career opportunities. To address the cancer research workforce gap, we propose the Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program, which will recruit cohorts of undergraduate students and provide them with research skills-building and mentored research experiences in cancer research. We will provide evidence-based professional development activities and sustained engagement through virtual platforms and the opportunity for program alumni to return in peer-to-peer mentor roles. The Duke PRIME: Cancer Research Program will achieve our long-term goal, addressing barriers that limit the recruitment and retention of a cancer research workforce through early exposure to intensive research experiences, an innovative didactics curriculum, and peer networking. The program focuses on 1) providing a mentored summer research intensive experience for undergraduates; 2) providing a parallel OPSD PRIME Academy enrichment curriculum to enhance understanding of FDQFHU research concepts and career paths in research; and 3) developing a peer networking model with sustained engagement throughout the academic year. Successful implementation of the proposed program will lead to a scalable model for development of a robust pipeline for a diverse biomedical research workforce across disciplines.