Transport and bioavailability of U and co-occurring metals in nanoparticulate matter on tribal lands affected by mining legacy

项目2-环境项目2-ESE颗粒(ESE PM)-项目摘要 位于纳瓦霍民族和拉古纳普韦布洛部落土地上的废弃铀矿 是环境污染的主要来源，其结果是威胁公众健康 动员含铀(U)、钒(V)、铜(Cu)、砷(As)的有毒金属混合物。这个 以纳米颗粒形式将有毒金属混合物输送到空气中，以及随后可能 吸入和摄入暴露，从来没有以严格的方式进行调查。建议数 研究将调查纳米颗粒中有毒金属混合物的潜在暴露危险 通过受污染的农作物吸入和摄取来自纳瓦霍民族和 拉古纳·普韦布洛部落位于亚利桑那州和新墨西哥州。该项目将解决两个具体目标： 1)了解一系列金属混合物的物理化学特征和分布 环境样本，包括矿山废物、土壤(农业和本底)和空气颗粒物 AUM周围，并模拟风向邻近社区的输送和沉积；2)评估 了解废弃矿场附近农业土壤上植物对金属的吸收情况 含有金属的颗粒物存在潜在的暴露风险。和3)了解其作用机制 作物根和叶系统对颗粒物同化的实验研究 开发含金属PM从AUM站点再悬浮和运输到AUM站点的过程模型 估计附近脆弱社区的暴露风险。对于流程模型，我们将a)确定 来自AUM场地和矿场的含金属PM的粒度分布和矿物学特征 在不同气象条件下对生活在区域空域中的脆弱人群的暴露潜力 条件；以及b)对该区域进行源-受体建模，整合来自三个区域的信息 表演网站，并得出纳瓦霍社区成员的长期估计。拟议的研究 将利用最先进的监测、化学、成像和大气建模技术提供 关于超细颗粒PM的浓度、形态、价态、溶解度等的综合数据集 评估PM的潜在毒性和吸入暴露风险所必需的纳米颗粒尺度这个 结果将减少有关AUM的金属含量、暴露浓度和来源的不确定性- 降低风险策略中与PM相关的暴露。

PROJECT 2 - ENVIRONMENTAL PROJECT 2 – ESE Particulate (ESE PM) - PROJECT SUMMARY Abandoned uranium mines (AUM) situated on the tribal lands of the Navajo Nation and Laguna pueblo represent a major source of environmental contamination that threatens public health as a result of mobilization of toxic metals mixtures bearing uranium (U), vanadium (V), copper (Cu), arsenic (As). The transport of toxic metals mixtures into the air in nanoparticulate form, and the subsequent potential for inhalational and ingestion exposures, has never been investigated in a rigorous manner. The proposed research will investigate the potential exposure hazards to toxic metals mixtures in nanoparticulates resulting from inhalation and ingestion via contaminated agricultural crops from AUM sites located on Navajo Nation and Laguna Pueblo tribal lands in Arizona and New Mexico. The project will address the two specific aims: 1) Understanding the physicochemical characteristics and distribution of metals mixtures in a range of environmental samples, including mine wastes, soils (agricultural and background) and airborne particulates around AUM and modelling their transport and deposition by wind into neighboring communities; 2) Assessing the uptake of metals into plants on agricultural soils adjacent to abandoned mine sites to understand if airborne metals-bearing particulates present a potential exposure risk. and 3) understanding the mechanisms of particulate assimilation into agricultural crops through their root and folial system through experimental stDeveloping a process model for the resuspension and transport of metal-bearing PM from AUM sites to estimate exposure risks for nearby vulnerable communities. For the process model, we will a) ascertain the particle size distributions and mineralogic characteristics of metal-bearing PM originating from AUM sites and the exposure potential to vulnerable populations living in the regional airshed under varied meteorological conditions; and b) conduct source-receptor modeling for the region, integrating information from three performance sites and deriving long-term estimates for Navajo community members. The proposed research will utilize state-of-the-art monitoring, chemical, imaging and atmospheric modeling techniques to provide a comprehensive dataset on the concentrations, speciation, valence, solubility, etc., of ultrafine-grained PM nanoparticle scale that are essential to evaluate the potential toxicity and inhalation exposure risk for PM. The results will reduce uncertainty regarding the metal content, exposure concentrations, and sources of AUM- related PM exposures in risk reduction strategies.