Administrative Core

引言 评论1和2指出，与外部行政首长协调委员会(行政首长协调委员会)和 明确指出和描述内部(IAB)咨询委员会。还有人建议， 每年举行由EAB、IAB和PPG项目负责人参加的现场会议，目的是 评估个别项目的进展情况。如下所示(正文和表2)，我们计划举行一次 年度计划项目务虚会以及其他定期安排的、与PPG相关的经常性项目 开会。我们很抱歉没有在原始提交的材料中清楚地说明这一点。 核心A是行政核心，将被所有项目和科学核心利用。 行政核心将促进项目进行的研究，并将作为 该计划的管理中心。此核心将需要管理员的努力(33%的努力)来 处理和协调与项目管理相关的所有活动。海流 研究计划协调员是C.R.A.的Stacy Holloway女士，她将继续担任这一职务。 行政核心将由项目主任保罗·W·多奇博士领导。大卫博士 副项目主任Lambeth将担任行政核心副主任并协助 Doetsch博士担任各种行政职务。 在该方案项目(“细胞对遗传毒性应激”)的前一个支持期内，有两个 五个原创项目中有四个离开了埃默里大学。前项目3首席调查员沃尔夫勒姆 Siede博士被重新安置到德克萨斯大学健康科学中心。沃斯·德克萨斯在第一场比赛结束时 资助年；Gerald Shadel，项目1首席研究员调往纽黑文的耶鲁大学 康涅狄格州在计划项目赠款的第二年。这是该计划的责任 管理人协助建立分包合同，并确保 调查人员没有受到这些举措的影响。Holloway女士协助及时提交所有 年度进度报告，外部顾问委员会成员访问耶鲁埃默里大学 大学和德克萨斯大学健康科学中心在福特。价值得克萨斯以及协调 每两个月从设备核心向两个分包合同发运准备好的介质。此外，它是 霍洛威女士负责组织和协调竞争性续签申请。 行政核心的活动将继续包括协调委员会的每月会议。 项目教员和研究小组每月的项目研究报告，包括 项目1至4加上小鼠肿瘤模型核心。活动包括但不限于 协调教员和实验室研究小组的日程安排，计划和执行会议和 会议纪要和摘要的生成、差旅和预订计划以及预算管理。 其他活动将包括安排和执行与内部咨询的季度会议 董事会和方案项目学院。安排访问和与外部咨询人的沟通 董事会也将由核心A负责。此类会议的目的将是审查计划 项目成就，讨论个别项目的重点和方向的重大变化，并 提供与项目相互关系相关的一般建议和反馈。此外，正如在 前一支持期间，在每月的计划项目领导会议上，讨论计划 资源问题(预算、计划管理员工作的利用率以及其他适当的问题) 地点。 行政核心负责编制和维护计划项目的总体记录，并编制 与计划活动相关的报告，包括进度报告和会议摘要。其他功能 包括计划通信、进度报告、手稿和其他出版物。霍洛威女士 还直接协助准备由项目2生成的手稿，并协助其他 行政礼仪。 行政核心位于罗林斯研究中心4027号，靠近Doetsch博士的办公室， 兰贝斯和格劳斯，并为秘书和其他行政活动提供了充分的装备。该项目 计划各组成部分对管理核心的使用如表1--核心A所示， 下面。

Introduction It was noted in Critiques 1 and 2 that the regularity and function of meetings with the External (EAB) and Internal (IAB) Advisory Boards be clearly indicated and described. It was also recommended that one annual, on-site meeting involving the EAB, IAB and PPG project leaders be held for the purpose of evaluating the progress of individual projects. As indicated below (text and Table 2), we plan to hold one annual Program Project retreat in addition to the other regularly scheduled, recurring PPG-related meetings. We apologize for not making this clear in the original submission. Core A is the Administrative Core and will be utilized by all projects and the Scientific Core. The Administrative Core will facilitate the research conducted by the projects and will serve as the administration center for the Program. This core will require the effort of an administrator (33% effort) to handle and coordinate all of the activities related to the administration of the Program. The current Research Program Coordinator is Ms. Stacy Holloway, C.R.A., who will continue to function in this role. The Administrative Core will be under the direction of Dr. Paul W. Doetsch, the Program Director. Dr. David Lambeth, the Deputy Program Director will function as vice director of the Administrative Core and assist Dr. Doetsch in various administrative capacities. During the previous support period of the Program Project ("Cellular Responses to Genotoxic Stress"), two of the five original projects left Emory University. The former Project 3 Principal Investigator, Wolfram Siede, relocated to the University of Texas Heath Sciences Center in Ft. Worth Texas at the end of the first year of the grant; Gerald Shadel, Project 1 Principal Investigator relocated to Yale University in New Haven Connecticut during year 2 of the Program Project Grant. It was the responsibility of the Program Administrator to assist with the establishment of the subcontracts and insure that communication between the investigators was not affected by the moves. Ms. Holloway facilitated the timely submission of all yearly progress reports, visits from the External Advisory board members to Emory University, Yale University and the University of Texas Heath Sciences Center in Ft. Worth Texas as well as coordination of bi-monthly shipments of prepared media to both subcontracts from the Equipment Core. Additionally, it is the responsibility of Ms. Holloway to organize and coordinate the Competitive Renewal Application. The activities of the Administrative Core will continue to include coordination of the monthly meetings of the Program faculty and the monthly Program research presentations by the research groups comprising Projects 1 through 4 plus the Mouse Tumor Models Core. Activities include, but are not limited to coordination of faculty and laboratory research group schedules, planning and executing meetings and generation of meeting minutes and summaries, travel and reservation planning and budget administration. Other activities will include the scheduling and execution of quarterly meetings with the Internal Advisory Board and the Program Project Faculty. Scheduling visits and communication with the External Advisory Board will also be the responsibility of Core A. The purposes of such meetings will be to review Program Project accomplishments, discuss significant changes in focus and direction of individual projects and to provide general advice and feedback related to project interrelationships. In addition, as was done during the previous support period, at the monthly Program Project Leaders' meeting, discussion of Program resource issues (budget, utilization of Program administrator effort, and other appropriate issues) will take place. The Administrative Core prepares and maintains the overall records for the Program Project and prepares reports related to Program activities, including Progress Reports and meeting summaries. Other functions include Program correspondence, Progress Reports, manuscripts and other publications. Ms. Holloway also directly assists in the preparation of manuscripts generated from Project 2 and assists in other administrative manners. The Administrative Core is located in 4027 Rollins Research Center, nearby to the offices of Drs. Doetsch, Lambeth and Grouse and is fully equipped for secretarial and other administrative activities. The project use of the Administrative Core by the various components of the Program are shown in Table 1-CORE A, below.