Pediatric Rheumatology Training Grant

描述（由申请人提供）： 这项培训补助金提案寻求支持，以准备个人（MD，MD/PhD或PhD）在生物医学科学的职业生涯，因为它涉及到儿科和成人流变学。该计划基于一个大型的风湿病学（儿科）部门，有几个中心赠款（P30，P60，PO 1）和NIH资助的研究人员，以及一个扩大的风湿病学（成人）部门的参与，该部门也有强大的NIH资金。儿科部门，包括其相关诊所，是辛辛那提儿童医院医疗中心（CCHMC）和儿童医院研究基金会（TCHRF）的一部分，也是辛辛那提大学医学院（UCCOM）及其临床和生物医学科学系的一部分。 成人部是UCCOM医学系的一部分，与儿科部以及CCHMC和UCCOM的免疫生物学研究人员有着密切的联系。主要的教师顾问不仅来自儿科系（流变学，过敏/免疫学，实验血液学，血液学/肿瘤学，人类遗传学，免疫生物学，信息学，分子免疫学和心理学）和医学系（免疫学和传染病），而且来自环境卫生和病理学部门，涵盖广泛的专业领域。这些包括免疫生物学，基因组学和生物信息学，基因表达，分子和发育生物学，基因治疗，干细胞生物学，流行病学和生物统计学，以及肌肉骨骼生物力学。除了儿科风湿病学的持续扩展外，CCHMC，UCCOM和TCHRF在本培训补助金的五年周期内也有相当大的增长，特别是在免疫生物学，实验血液学和生物信息学方面。该计划得到了核心设施和学术课程的大力支持，包括医学伦理学的必修课程。其他课程包括免疫生物学、分子遗传学、流行病学和生物统计学。一个新的跨部门的免疫生物学研究生课程（MS和博士），是集中在CCHMC补充现有的流行病学和生物统计学，并在UCCOM教育计划。据信，这个流变学计划提供了独特的资源，并将继续扩大个人的职业兴趣，在生物医学科学，因为它涉及到亚专业，这是太小，以满足未来几十年的要求，作为分子医学越来越多地应用于临床。

DESCRIPTION (provided by applicant): This training grant proposal seeks support to prepare individuals (MD, MD/PhD, or PhD) for a career in biomedical science as it relates to pediatric and adult rheumatology. The program is based in a large Division of Rheumatology (Pediatric), with several center grants (P30, P60, PO1) and NIH-funded investigators with the participation of an enlarging Division of Rheumatology (Adult) that also has strong NIH funding. The Pediatric Division, including its related clinic, is part of Cincinnati Children's Hospital Medical Center (CCHMC) and The Children's Hospital Research Foundation (TCHRF), as well as part of the University of Cincinnati College of Medicine (UCCOM) with its clinical and biomedical science departments. The Adult Division is part of the Department of Medicine of UCCOM and has strong ties to the Pediatric Division and to immunobiology researchers at CCHMC and UCCOM. The primary faculty advisors come not only from divisions within the Department of Pediatrics (Rheumatology, Allergy/Immunology, Experimental Hematology, Hematology/Oncology, Human Genetics, Immunobiology, Informatics, Molecular Immunology, and Psychology) and the Department of Medicine (Immunology and Infectious Disease) but also from the Departments of Environmental Health, and Pathology, and cover broad areas of expertise. These include immunobiology, genomics and bioinformatics, gene expression, molecular and developmental biology, gene therapy, stem cell biology, epidemiologist and biostatistics, and musculoskeletal biomechanics. In addition to continued expansion in pediatric rheumatology, CCHMC, UCCOM, and TCHRF have also seen considerable growth during the present five-year cycle of this training grant, particularly in immunobiology, experimental hematology, and bioinformatics. The program is well supported by core facilities as well as by academic courses, including a mandatory course in medical ethics. Other available courses include immunobiology, molecular genetics, and epidemiology and biostatistics. A new interdepartmental Immunobiology Graduate Program (MS and PhD) that is centered at CCHMC complements existing programs in Epidemiology and Biostatistics, and Education in the UCCOM. It is believed that this rheumatology program provides unique resources and will continue to enlarge the pool of individuals with a career interest in biomedical science as it relates to the subspecialties, a pool that is far too small to meet the requirements of the next decades as molecular medicine is increasingly applied in the clinic.