University of Louisville Bioinformatics Faculty Recruitment for Epigenetics

描述（由申请人提供）：这是一个为生物信息学教授提供资金的请求，在表观遗传学方面有专长。这一要求是由路易斯维尔大学酒精研究中心（ULARCNIAAA资助的P01AA017103-01-Craig McClain， PI）提出的，新的教师队伍将在临床和转化科学研究所的生物医学和健康信息学核心和医学院。合作中心/研究所是路易斯维尔大学环境遗传学和综合生物学中心（CEGIB- NIEHS P30 ES014443, Ken Ramos， PI）；路易斯维尔大学临床与转化科学研究所（CTSI, Craig McClain，主任）；糖尿病与肥胖研究卓越中心（P20RR024489-01A1, Aruni Bhatnagar， PI）；环境醛的心血管毒性（P01ES011860-05, Aruni Bhatnagar， PI）。UofL的生物信息学工作组确定了UofL未来十年的生物信息学能力和需求。他们推荐了10条教员路线。该教师招聘将填补2007年提供给CTSI的三个生物信息学教师队伍中的一个，并在之前的广告中公布。补助金完成后，将提供两年的薪金支助。该教员职位的主要目标是捕捉参与者的环境（例如酒精和营养）、医疗和行为方面；将它们合并到一个可用的数据库中；将这些信息与研究者的表观遗传数据中的研究信息相结合；与其他研究人员和中心合作；并整合来自国家登记处和数据库的数据。生物信息学职位将与路易斯维尔大学酒精研究中心和临床和转化科学研究所一起位于临床和转化科学大楼。所有的支持服务、计算机系统、数据库等都是可用的，或者可以从这个位置访问。终身教职、晋升和职业发展都发生在医学院。麦克莱恩博士是这项资助的项目负责人，他在指导新教师方面有着典范的记录，获得了20多项职业发展奖项，即K奖。在健康科学中心研究办公室的额外帮助下，学校有一个完善的指导和新的教师援助计划。评估将包括核心和教员。CTSI将对核心进行评估，而麦克莱恩博士和系主任将根据工作分配合同对教员进行评估。

DESCRIPTION (provided by applicant): This is a request to provide funding for a bioinformatics faculty member with a specialty in epigenetics. This request is put forward by the University of Louisville Alcohol Research Center (ULARCNIAAA- funded P01AA017103-01-Craig McClain, PI) and the new faculty line will be in the Clinical and Translational Sciences Institute's Biomedical and Health Informatics Core and the School of Medicine. Collaborating Centers/Institutes are the University of Louisville Center for Environmental Genetics and Integrative Biology (CEGIB- NIEHS P30 ES014443, Ken Ramos, PI); the University of Louisville Clinical and Translational Sciences Institute (CTSI, Craig McClain, Director); the Center of Excellence in Diabetes and Obesity Research (P20RR024489-01A1, Aruni Bhatnagar, PI); and Cardiovascular Toxicity of Environmental Aldehydes (P01ES011860-05, Aruni Bhatnagar, PI). UofL's Bioinformatics Task Force defined UofL bioinformatics capacity and needs for the next ten years. They recommended ten faculty lines. This faculty hire will fill one of the three bioinformatics faculty lines provided to the CTSI in 2007 and previously advertised. Two years of salary support has been provided after the completion of the grant. The primary objectives of this faculty position are to capture the environmental (examples; alcohol, and nutrition), medical and behavioral aspects of participants; incorporate them into a usable database; integrate that information with the research information available from the investigator's epigenetic data; collaborate with the other investigators and centers; and integrate data from national registries and databases. The bioinformatics position will physically be located with the University of Louisville Alcohol Research Center and the Clinical and Translational Sciences Institute in the Clinical and Translational Sciences Building. All support services, computer systems, databases, etc. are either available or can be accessed from this location. Tenure, promotion and career development occur in the School of Medicine. Dr. McClain the PI on this grant has an exemplary tract record for mentoring new faculty with over 20 career development awards, i.e. K awards. The school has a well established mentoring and new faculty assistance program with additional assistance from the Health Sciences Center Research Office. Evaluation will include the core and the faculty member. The CTSI will evaluate the Core while Dr. McClain and the department chair using the work assignment contract will evaluate the faculty member. PUBLIC HEALTH RELEVANCE: Filling this bioinformatics faculty line is essential for UL developing an epigenetics focus and the continued success of all centers included in this submission.