Colorado Career Development Program in the Genetics and Genomics of Lung Diseases

描述（由申请人提供）： 认识到遗传学和基因组学技术应用于人类疾病的日益重要性，并意识到肺病研究可以从这些技术的扩展使用中受益的程度，我们提出了科罗拉多肺遗传学和基因组学计划（CPGGP），用于肺遗传学和基因组学研究学者的职业发展。拟议的职业发展计划的目标：培训领导者在肺部疾病遗传学和基因组学临床研究领域建立一个课程结合我们现有的最好的肺医学培训，人类医学遗传学和临床科学计划增加合作招募来自不同背景的优秀学者我们拟议的计划响应NHLBI蓝图，并有以下组件实现这些目标：该课程旨在使所有学者对肺部疾病遗传学和基因组学研究的基本原理和现实有相应的了解，无论他们的背景如何，通过在四种主要肺部疾病之一进行遗传学和/或基因组学研究的研究机会，急性肺损伤/急性呼吸窘迫综合征（ALI/ARDS）、肺动脉高压（PH）、慢性阻塞性肺疾病/癌症预防（COPD/CA），和肉芽肿性肺病合作通过共同指导的研究项目通过临床研究设计、监管监督等方面的培训为独立临床研究做好准备，资助写作，人类受试者的使用，以及人类医学遗传学研究中固有的伦理学计划评估和学员随访该计划吸收了肺部疾病，医学遗传学，生物信息学和临床科学培训计划的专业知识，以便为学者提供机会，使他们有机会在计划中做出重大选择，并优化他们未来的成功。在目前的模式下，不仅学者将受益，但导师也将通过参与该计划获利。通过更广泛地涵盖选定的肺部疾病，该计划可以对遗传学和基因组学在肺部疾病中的应用产生显著影响。 (End摘要）

DESCRIPTION (provided by applicant): In recognition of the growing importance of genetics and genomics techniques applied to human disease, and in awareness of the extent to which lung disease research could benefit from expanded use of these technologies, we propose the Colorado Pulmonary Genetics and Genomics Program (CPGGP) for the career development of scholars in pulmonary genetics and genomics research. Objectives of the proposed career development program: Train leaders in the field of clinical research in lung disease genetics and genomics Build a curriculum combining the best of our existing pulmonary medicine training, human medical genetics, and clinical sciences programs Increase collaboration Recruit excellent scholars from various backgrounds Our proposed program responds to the NHLBI blueprint and has the following components for achieving these objectives: A curriculum designed to bring all scholars to a commensurate understanding of the fundamentals and realities of lung disease genetics and genomics research, regardless of their background Breadth of study through research opportunities in ongoing genetics and/or genomics research in one of four major lung diseases: Acute Lung Injury / Acute Respiratory Distress Syndrome (ALI/ARDS), Pulmonary Hypertension (PH), Chronic Obstructive Pulmonary Disease / Cancer Prevention (COPD/CA), and Granulomatous Lung Disease Collaboration through co-mentored research projects Preparation for independent clinical research through training in clinical research design, regulatory oversight, grant writing, human subject use, and ethics inherent in human medical genetics research Program evaluation and trainee follow-up The Program assimilates the expertise resident in Pulmonary Diseases, Medical Genetics, Bioinformatics, and the Clinical Sciences Training Program in order to afford Scholars the opportunity for significant choices regarding their journey through the Program, and optimizing their future success. In the current paradigm, not only will Scholars benefit, but Mentors will also profit through their involvement in the Program. By more broadly covering selected Pulmonary Diseases, the Program can have a pronounced impact on the application of genetics and genomics to lung diseases. (End of Abstract)