Neural trajectories towards vulnerability versus resilience: A longitudinal twin study

韧性不仅定义了没有精神障碍；它定义了面对逆境积极适应的能力。由于这种概念上的模糊性，与抑郁和焦虑等症状相比，人们对其潜在的神经生物学知之甚少。这一知识将有助于创伤暴露后有效干预措施的发展。我们的目标是在270名成年人中定义弹性的第一个神经剖面，使用双胞胎方法来确定新的基因-环境影响。

Resilience not only defines the absence of mental disorder; it defines the ability to positively adapt in the face of adversity. Due to this conceptual ambiguity, little is known of its underlying neurobiology as compared to symptoms like depression and anxiety. This knowledge would aid the development of effective interventions following trauma exposure. We aim to define the first neural profile of resilience in 270 adults, using the twin method to decide novel gene-environment influences.