Intervention Development and Pilot Study to Prevent Untreated Native Hawaiian and Pacific Islander Opioid Use Disorders

项目摘要 太平洋岛民是一个研究不足的美国种族群体，他们在药物使用方面存在严重的差异， 并具有极高的甲基苯丙胺使用障碍(MUD)和由此导致的社会、经济、 对健康有害。然而，我们对太平洋岛民社区中MUD的原因和驱动因素知之甚少； 这限制了我们设计有效的干预措施来预防和治疗高危太平洋岛民的泥浆的能力。至 通报制定有效的甲基苯丙胺预防和治疗工作的情况 人口，这份多样性补充的目标是通过以下方式提高我们对太平洋岛民的认识 定性探讨太平洋岛民的主要风险和保护性因素，以及治疗障碍 MUDS，并利用这一新的数据设计了一个基于文化的治疗寻求概念模型 针对携带泥浆的太平洋岛民的干预组件。具体地说，在研究的第一年，多样性 补充候选人-太平洋岛民遗产职业生涯早期的一名女性社会工作学院-将进行 太平洋岛民MUDS的四个重点小组定性调查他们的治疗寻求障碍 和促进者，以及风险和保护因素。在第二年，候选人将使用她导师建立的 改进的德尔菲法设计泥浆治疗-寻求干预组件概念模型 针对NHPI，并领导4个焦点小组使用来自Layer的反馈来验证和塑造这些组件 带着泥浆的NHPI。建立在父母赠款的基础上(重点是解决太平洋地区的阿片使用障碍 岛民)，本附录的目的是支持候选人(1)实施第一种混合方法 研究太平洋岛民中的MUDS，以及(2)获得强化培训和指导，以成为 太平洋岛民药物使用预防和干预研究方面的领先权威。 由美国国立卫生研究院资助的太平洋岛民物质使用和研究人员组成的指导团队提供支持 健康差距，候选人将获得关键技能的物质使用流行病学，预防和 干预研究方法，以社区为基础的参与性研究，以及手稿和赠款的撰写。 基于她对NIDA多样性补编的结构化研究和培训经验， 候选人将在资助期结束时申请NIDA K01奖助金。

PROJECT ABSTRACT Pacific Islanders are an understudied U.S. racial group that endures severe disparities in substance use, and bears exceptionally high risk for methamphetamine use disorders (MUD) and resulting social, economic, and health harms. Yet, we know little about the causes and drivers of MUDs in Pacific Islander communities; restricting our ability to design effective interventions to prevent and treat MUDs in at-risk Pacific Islanders. To inform the development of effective methamphetamine prevention and treatment efforts for this understudied population, the goals of this Diversity Supplement are to improve our knowledge of Pacific Islander MUDs by qualitatively exploring the major risk and protective factors, and barriers to treatment, in Pacific Islanders with MUDs, and using this novel data to design a conceptual model of culturally grounded treatment-seeking intervention components for Pacific Islanders with MUDs. Specifically, in Year 1 of the study, the Diversity Supplement candidate—a female, early career social work faculty of Pacific Islander heritage—will conduct four focus groups of Pacific Islanders with MUDs to qualitatively investigate their treatment seeking barriers and facilitators, and risk and protective factors. In Year 2, the candidate will use her mentor’s established modified Delphi approach to design a conceptual model of MUD treatment-seeking intervention components for NHPIs and conduct 4 focus groups to validate and shape these components using feedback from lay NHPIs with MUDs. Building off the parent grant (which is focused on addressing opioid use disorders in Pacific Islanders), the goal of this supplement is to support the candidate in (1) conducting the first mixed methods study of MUDs among Pacific Islanders, and (2) obtaining intensive training and mentorship to become a leading authority on substance use prevention and intervention research with Pacific Islander populations. Supported by a mentoring team of established NIH-funded researchers in Pacific Islander substance use and health disparities, the candidate will gain critical skills in substance use epidemiological, prevention, and intervention research approaches, community-based participatory research, and manuscript and grant-writing. Building upon her structured research and training experiences on this NIDA Diversity Supplement, the candidate will apply for a NIDA K01 grant at the end of the funding period.