Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults

预防太平洋岛民年轻人的酒精使用障碍和酒精相关危害

• 批准号: 10804296
• 负责人: Andrew Makoto Subica
• 金额: $ 60.54万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-18 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10804296
• 关键词: Adoption; Affect; Alcohol abuse; Alcohol consumption; Alcohols; Arkansas; Asian Americans; Attention; Communities; Consensus; Country; County; Decision Making; Disparity; Feedback; Funding; General Population; Health; Health Care Costs; Home; Intervention; Intervention Studies; Los Angeles; Manuals; Manuscripts; Methodology; Modeling; National Institute on Alcohol Abuse and Alcoholism; Native Hawaiian; Pacific Islander; Pattern; Policy Maker; Polynesian; Pre-Post Tests; Prevention; Prevention Research; Prevention strategy; Provider; Public Health; Randomized; Randomized, Controlled Trials; Reporting; Research; Research Methodology; Risk; Rural; Science; Shapes; Social Development; Subgroup; Substance Use Disorder; Testing; United States National Institutes of Health; Work; active control; alcohol prevention; alcohol related problem; alcohol research; alcohol use disorder; binge drinking; community based participatory research; community engaged research; community intervention; design; deter alcohol use; disorder prevention; disorder risk; effective intervention; efficacy evaluation; efficacy testing; empowerment; evidence base; experience; feasibility testing; follow-up; hazardous drinking; high risk; high risk drinking; high risk population; implementation study; innovation; migration; model development; multi-component intervention; novel; pilot test; prevent; preventive intervention; primary outcome; protective factors; racial population; reduced alcohol use; social; therapy design; treatment services; trial design; young adult

Abstract Native Hawaiians/Pacific Islanders (NPI) in the U.S. are a rapidly growing racial group that suffers severe alcohol-related disparities. In NPI communities, young adults (18-30 years) endure the greatest burden of alcohol use disorders (AUD) and alcohol-related harms with our earlier NIAAA R21 study revealing that almost 50% of community-dwelling NPI young adults are at heavy risk for, or have, AUDs with 40% experiencing alcohol-related harms (e.g., health, social, work). Despite this, NPI young adults have received minimal alcohol research attention, leading to a lack of effective interventions to prevent or reduce their extreme AUD risk. Guided by the findings of our NIAAA R21, this resubmitted R01 study will respond to this public health gap by refining and efficacy testing SPEAR (Strategies for Pacific Empowerment and Alcohol Reduction): a novel culturally grounded AUD prevention intervention for NPI young adults. Building on our R21-developed Model of SPEAR intervention components for NPI young adults (previously chosen and shaped in our R21 by NPIs from existing AUD prevention interventions), in Aim 1, we will assemble our treatment manual from our NPI-shaped R21 AUD prevention components. To assemble the manual, we will use our culturally congruent intervention design methodology for NPIs involving an Advisory Council of community experts and citizens’ panels—an innovative research approach that mirrors NPI collective decision-making practices—to obtain critical feedback for refining SPEAR content/components from NPI young adults with high AUD risk and informal NPI providers. In Aim 2, we will review and refine our treatment components and manual through expert review by 3 leading alcohol research experts and feasibility pilot test the manual with 36 NPI young adults with high AUD risk for feasibility, acceptability, and impact, using our findings to finalize SPEAR for our randomized controlled trial. In Aim 3, we will test the efficacy of SPEAR by conducting a full-scale randomized controlled trial with 240 NPI young adults with high AUD risk in two large NPI communities in Los Angeles County and Northwest Arkansas for generalizability. Aligning with community research principles, we will share study findings with the NPI community through public reports and presentations, and to the scientific community through academic presentations and manuscripts.

抽象的 美国的夏威夷原住民/太平洋岛民 (NPI) 是一个快速增长的种族群体，遭受着严重的 与酒精相关的差异。在 NPI 社区中，年轻人（18-30 岁）承受着最大的酒精负担 我们早期的 NIAAA R21 研究表明，近 50% 的人使用障碍 (AUD) 和酒精相关的危害 居住在社区的 NPI 年轻人面临 AUD 的严重风险或患有 AUD，其中 40% 的人经历过与酒精相关的经历 危害（例如健康、社会、工作）。尽管如此，NPI 年轻人接受的酒精研究很少 的关注，导致缺乏有效的干预措施来预防或降低其极端澳元风险。 在我们的 NIAAA R21 研究结果的指导下，这项重新提交的 R01 研究将应对这一公共卫生差距 通过改进和功效测试SPEAR（太平洋赋权和酒精减少战略）：一种新颖的 针对 NPI 年轻人的基于文化的 AUD 预防干预。基于我们 R21 开发的模型 针对 NPI 年轻人的 SPEAR 干预组成部分（之前由来自以下国家的 NPI 在我们的 R21 中选择和塑造） 现有的 AUD 预防干预措施），在目标 1 中，我们将从我们的 NPI 形状中汇编我们的治疗手册 R21 AUD 预防组件。为了编写手册，我们将使用文化一致的干预措施 涉及社区专家咨询委员会和公民小组的非营利机构的设计方法—— 反映 NPI 集体决策实践的创新研究方法——获取关键反馈 用于提炼来自具有高 AUD 风险的 NPI 年轻人和非正式 NPI 提供商的 SPEAR 内容/组件。 在目标 2 中，我们将通过 3 位领先的专家评审来审查和完善我们的治疗组件和手册。 酒精研究专家和可行性试点对 36 名具有高 AUD 风险的 NPI 年轻人测试了该手册 可行性、可接受性和影响，利用我们的研究结果最终确定 SPEAR 的随机对照试验。在 目标3，我们将通过240个NPI进行全面随机对照试验来测试SPEAR的功效 洛杉矶县和阿肯色州西北部两个大型 NPI 社区中 AUD 风险较高的年轻人 为了具有普遍性。符合社区研究原则，我们将与 NPI 分享研究结果 通过公开报告和演示向社区提供信息，并通过学术界向科学界提供信息 演示文稿和手稿。