Preventing Alcohol Use Disorders and Alcohol-Related Harms in Pacific Islander Young Adults

预防太平洋岛民年轻人的酒精使用障碍和酒精相关危害

• 批准号: 10804296
• 负责人: Andrew Makoto Subica
• 金额: $ 60.54万
• 依托单位: UNIVERSITY OF CALIFORNIA RIVERSIDE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-18 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10804296
• 关键词: Adoption; Affect; Alcohol abuse; Alcohol consumption; Alcohols; Arkansas; Asian Americans; Attention; Communities; Consensus; Country; County; Decision Making; Disparity; Feedback; Funding; General Population; Health; Health Care Costs; Home; Intervention; Intervention Studies; Los Angeles; Manuals; Manuscripts; Methodology; Modeling; National Institute on Alcohol Abuse and Alcoholism; Native Hawaiian; Pacific Islander; Pattern; Policy Maker; Polynesian; Pre-Post Tests; Prevention; Prevention Research; Prevention strategy; Provider; Public Health; Randomized; Randomized, Controlled Trials; Reporting; Research; Research Methodology; Risk; Rural; Science; Shapes; Social Development; Subgroup; Substance Use Disorder; Testing; United States National Institutes of Health; Work; active control; alcohol prevention; alcohol related problem; alcohol research; alcohol use disorder; binge drinking; community based participatory research; community engaged research; community intervention; design; deter alcohol use; disorder prevention; disorder risk; effective intervention; efficacy evaluation; efficacy testing; empowerment; evidence base; experience; feasibility testing; follow-up; hazardous drinking; high risk; high risk drinking; high risk population; implementation study; innovation; migration; model development; multi-component intervention; novel; pilot test; prevent; preventive intervention; primary outcome; protective factors; racial population; reduced alcohol use; social; therapy design; treatment services; trial design; young adult

Abstract Native Hawaiians/Pacific Islanders (NPI) in the U.S. are a rapidly growing racial group that suffers severe alcohol-related disparities. In NPI communities, young adults (18-30 years) endure the greatest burden of alcohol use disorders (AUD) and alcohol-related harms with our earlier NIAAA R21 study revealing that almost 50% of community-dwelling NPI young adults are at heavy risk for, or have, AUDs with 40% experiencing alcohol-related harms (e.g., health, social, work). Despite this, NPI young adults have received minimal alcohol research attention, leading to a lack of effective interventions to prevent or reduce their extreme AUD risk. Guided by the findings of our NIAAA R21, this resubmitted R01 study will respond to this public health gap by refining and efficacy testing SPEAR (Strategies for Pacific Empowerment and Alcohol Reduction): a novel culturally grounded AUD prevention intervention for NPI young adults. Building on our R21-developed Model of SPEAR intervention components for NPI young adults (previously chosen and shaped in our R21 by NPIs from existing AUD prevention interventions), in Aim 1, we will assemble our treatment manual from our NPI-shaped R21 AUD prevention components. To assemble the manual, we will use our culturally congruent intervention design methodology for NPIs involving an Advisory Council of community experts and citizens’ panels—an innovative research approach that mirrors NPI collective decision-making practices—to obtain critical feedback for refining SPEAR content/components from NPI young adults with high AUD risk and informal NPI providers. In Aim 2, we will review and refine our treatment components and manual through expert review by 3 leading alcohol research experts and feasibility pilot test the manual with 36 NPI young adults with high AUD risk for feasibility, acceptability, and impact, using our findings to finalize SPEAR for our randomized controlled trial. In Aim 3, we will test the efficacy of SPEAR by conducting a full-scale randomized controlled trial with 240 NPI young adults with high AUD risk in two large NPI communities in Los Angeles County and Northwest Arkansas for generalizability. Aligning with community research principles, we will share study findings with the NPI community through public reports and presentations, and to the scientific community through academic presentations and manuscripts.

摘要 夏威夷原住民/太平洋岛民(NPI)在美国是一个迅速增长的种族群体，患有严重的 与酒精相关的差异。在NPI社区，年轻人(18-30岁)承受着最大的酒精负担 使用障碍(AUD)和与酒精相关的危害与我们早期的NIAAA R21研究显示，近50%的 居住在社区的NPI年轻人患有或患有AUD的风险很高，其中40%的人经历过与酒精相关的疾病 危害(例如，健康、社会、工作)。尽管如此，NPI的年轻人已经接受了最低限度的酒精研究 这导致缺乏有效的干预措施来预防或降低其极端的非典风险。 在我们NIAAA R21研究结果的指导下，重新提交的R01研究将对这一公共卫生差距做出回应 通过提炼和有效性测试SPEAR(太平洋赋权和减少酒精战略)：一种新的 针对NPI青壮年的基于文化的澳大利亚缺乏症预防干预。以我们的R21开发模型为基础 针对NPI年轻人的长矛干预组件(在我们的R21中之前由NPI从 现有的AUD预防干预措施)，在目标1中，我们将从NPI形状的 R21 AUD预防组件。为了汇编这本手册，我们将使用我们的文化一致性干预 由社区专家和市民小组组成的咨询委员会参与的NPI的设计方法 反映NPI集体决策实践的创新研究方法--以获取批判性反馈 用于从具有高澳元风险的年轻人和非正式的NPI供应商提炼鱼叉内容物/成分。 在目标2中，我们将由3位领先者通过专家评审来审查和完善我们的治疗组件和手册 酒精研究专家和可行性试点对36名患有AUD高风险的NPI年轻人进行了手册测试 可行性、可接受性和影响，利用我们的研究结果最终确定我们的随机对照试验的SPAR。在……里面 目的3，我们将通过对240个NPI进行全面的随机对照试验来测试SPEAR的疗效 洛杉矶县和阿肯色州西北部两个大型NPI社区中有高AUD风险的年轻人 以求泛化。为配合社区研究的原则，我们会与国家创新中心分享研究结果。 通过公共报告和演讲向科学界，并通过学术报告向科学界 演讲和手稿。