2022 Sensory Transduction in Microorganisms GRC & GRS

项目总结 2022年戈登微生物感觉转导研究会议将在加利福尼亚州文图拉举行 2022年1月将探讨了解细菌信号转导的最新进展，特别是 病原体。重点将放在化学传感机制和途径，细胞内小分子 信号(如c-di-GMP)、两个组分系统及其调节的细胞过程 细菌生活方式决定的机制，包括生物膜、细菌多细胞行为和捕食者-猎物 互动。这些系统在发病机制、抗菌素耐药性和合成代谢方面的作用 生物学将是中心主题。这次会议的一个重要议题将是宿主与微生物的相互作用。所有这些都是 关键领域将通过分子遗传学、细胞生物学、 生物化学、化学生物学以及结构、成像、生物物理和计算方法。 来自高分辨率实验的数据将与建模配对，以了解和预测 复杂的大分子组件和信号电路。特邀演讲者将包括已建立的和 使用各种方法的早期调查人员。此外，简短的演讲将从 摘要，让更多的早期职业科学家有机会发言，并就该计划进行讨论。 与会者将受益于会议开放、合议的气氛，这种气氛提供了多种机会 参与科学讨论，促进科学严谨，促进跨学科合作。新的, 将利用创新努力，增加来自历史上代表性不足的科学家的参与 背景，并将采取多种努力，使与会者感到受欢迎和重视。这是第五次了 针对博士后和研究生的戈登研究研讨会(GRS)将在GRC之前举行。《全球资源报告》 为青年科学家提供一个展示他们的工作、建立联系和接受 来自该领域领导者的建议。STIM社区长期以来一直支持初级科学家，我们认为 GRS的成功是继续执行这项任务的必要条件。GRS将帮助我们不仅培养 发展早期调查人员，但也促进了我们社区的多样性。GRS将会有所帮助 初级科学家获得了成为成熟的GRC参与者的信心和技能。完美整合的 Stim GRC/GRS将指导现有的调查人员解决我们领域面临的最重要的问题 将鼓励年轻科学家将他们最近的培训应用于令人兴奋的微生物学新领域。

Project summary The 2022 Gordon Research Conference on Sensory Transduction in Microorganisms to be held in Ventura CA in January 2022 will explore recent advances in understanding signal transduction in bacteria, especially pathogens. Focus will be placed on chemosensory mechanisms and pathways, small molecule intracellular signals (e.g. c-di-GMP), two component systems and the cellular processes they regulate as well as mechanisms of bacterial lifestyle decisions including biofilms, bacterial multicellular behavior and predator-prey interactions. The roles of these systems with respect to pathogenesis, antimicrobial resistance, and synthetic biology will be central themes. An important topic for this conference will be host-microbe interactions. All these critical areas will be addressed through cutting-edge applications of molecular genetics, cell biology, biochemistry, and chemical biology as well as structural, imaging, biophysical, and computational approaches. Data from high-resolution experiments will be paired with modeling to understand and predict the behavior of complex macromolecular assemblies and signaling circuitry. Invited speakers will include both established and early-stage investigators using a wide array of approaches. In addition, short talks will be chosen from the abstracts to give additional early-career scientists a chance to speak, and to round on the program. Participants will benefit from the Conference's open, collegial atmosphere that provides multiple opportunities to engage in scientific discussion, promote scientific rigor, and foster interdisciplinary collaboration. New, innovative efforts will be used to increase participation of scientists from historically under-represented backgrounds, and multiple efforts will be taken to make participants feel welcome and valued. For the fifth time, a Gordon Research Seminar (GRS) for postdocs and graduate students will precede the GRC. The GRS provides a supportive environment for young scientists to present their work, make connections, and receive advice by leaders in the field. The STIM community has long supported junior scientists, and we view the success of the GRS as a necessity to continue on this mission. The GRS will help us not only nurture the development of early stage investigators, but also promote diversity within our community. The GRS will help junior scientists gain the confidence and skills to become full-fledged GRC participants. The well-integrated STIM GRC/GRS will direct established investigators to the most important questions confronting our field and will encourage young scientists to apply their recent training to the exciting new areas of microbiology.