Developmental Origins of Metabolic Disorders

摘要 密歇根大学的博士后儿科内分泌学和糖尿病培训项目是 旨在招募和提供两个主要轨道之一的高质量研究培训，基础科学或 临床调查和流行病学合格的候选人。今年是该方案的第15个年头，其主题是 葡萄糖代谢紊乱的发展规划。该计划的组织是为了补充 为医学博士和从事临床儿科内分泌学研究的基础科学家建立了临床儿科内分泌学培训计划， 内分泌相关研究的职业生涯，通过提供2年密集的博士后培训，使用密切- 为每个受训者单独制定的指导研究培训计划。该方案得到积极支持 由来自11个UM部门/学校的14名教师组成，所有人都具有丰富的研究和指导经验， 各自的专业领域。该计划还包括一个广泛的教学组成部分， 每个学员的教育背景和研究兴趣。开始基础科学研究的受训人员 完成为期3个月的课程，旨在让他们接触各种最先进的技术，以及 在执行假设驱动，控制研究的技能。临床研究与临床医学 流行病学选择结果和流行病学或临床研究。他们完成课程 导致无论是在生物统计学和流行病学公共卫生硕士或临床科学硕士 研究设计和统计分析。除了正式课程外，受训人员每周参加临床和 研究研讨会，接受指导准备和提供口头报告，并指导道德 进行研究。指导研究得到医学院资源的支持，包括 综合糖尿病研究，营养肥胖研究，器官发生，人类生长和 发展，综合代谢组学中心，分子和行为神经科学研究所和 密歇根临床与健康研究所。为了最大限度地发挥每个学员的潜力， 成功的学术生涯，受训者必须向国家会议提交摘要，提交第一份- 撰写研究论文，并申请个人资助。扩大我们的计划将有助于 缓解成功的儿科内分泌学家和儿科医生科学家的严重短缺。

Abstract The postdoctoral Pediatric Endocrinology and Diabetes Training Program at the University of Michigan is designed to recruit and provide high quality research training in one of two major tracks, Basic Science or Clinical Investigation & Epidemiology to qualified candidates. Now on its 15th year, the theme of the Program is developmental programming of disorders of glucose metabolism. The program is organized to complement the established training program in clinical pediatric endocrinology for M.D.s, and for basic scientists pursuing a career in endocrine related research, by providing 2 years of intensive postdoctoral training using a closely- mentored research training program individually structured for each trainee. The program is actively supported by 14 faculty from 11 UM Departments/Schools, all with extensive research and mentoring experience within their respective areas of expertise. The Program also includes an extensive didactic component tailored to each trainee’s educational background and research interests. Trainees initiating Basic Science research complete a 3-month course designed to expose them to a variety of state-of-the-art techniques, as well as to skills in performing hypothesis-driven, controlled research studies. Trainees in Clinical Investigation & Epidemiology choose between Outcomes & Epidemiology or Clinical Research. They complete courses leading to either a Master of Public Health in Biostatistics & Epidemiology or a Master of Science in Clinical Research Design & Statistical Analysis. In addition to the formal curriculum, trainees attend weekly clinical and research seminars, receive instruction preparing and delivering oral presentations, and instruction in ethical conduct of research. Mentored research is supported the Medical School resources including the Centers of Comprehensive Diabetes Research, Nutrition Obesity Research, Organogenesis, Human Growth and Development, Comprehensive Metabolomic Center, Molecular & Behavioral Neuroscience Institute and the Michigan Institute for Clinical and Health Research. To optimize each trainee’s potential for development of a successful academic career, trainees are required to submit abstracts to national meetings, submit a first- authored research manuscript, and apply for individual grant funding. Expansion of our Program will help alleviate the critical shortage of successful Pediatric Endocrinologists and Pediatric Physician-Scientists.