Pilot Projects and Trans-Network Activities Core

试点项目和跨网络活动核心--摘要 试点项目和跨网络活动核心的目标是支持研究的发展 使用PDX模型的项目将推进PDTC和PDXNet的使命。核心将有助于促进 通过在PDTC内部和跨PDXNet建立两个年度 五万美元奖金。这些得到支持的项目的目标将是支持PDTC的翻译目标 通过使用PDX模型或研究方法促进翻译研究，以增强实验 跨PDTC和PDXNet的验证和重复性。试点项目可能会支持发展和 将新技术融入PDXNet计划。还可以使用协作式、PDXNet试点项目 为跨网络研究建立使用PDX模型进行研究的最佳实践标准。核心意志 还与非PDXNet调查人员接洽，提供协作机会以使用功能齐全的PDX 这些模型概括了人类疾病，并进一步扩大了NCI PDXNet计划的覆盖范围。

PILOT PROJECTS AND TRANS-NETWORK ACTIVITIES CORE - SUMMARY The goal of the Pilot Projects and Trans-Network Activities Core is to support the development of research projects using PDX models that will advance the mission of the PDTC and PDXNet. The core will help to foster collaborative, translational research both within the PDTC and across the PDXNet by establishing two annual $50,000 awards. The goal of these supported projects will be to support the translational goals of the PDTC to advance translational research through the use of PDX models or, research methods to enhance experimental validation and reproducibility across PDTCs and the PDXNet. Pilot projects may support the development and integration of new technologies into the PDXNet program. Collaborative, PDXNet pilot projects may also be used for Cross-Network studies to establish best practice standards for research using PDX models. The Core will also engage non-PDXNet investigators, providing collaborative opportunities to use well-characterized PDX models that recapitulate human disease and further the reach of the NCI PDXNet program.