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中文摘要
翻译
项目摘要:动物服务核心 动物服务核心是为了满足研究人员对翻译研究不断发展的需求而构建的 通过提供资源来开发眼部疾病的实验动物模型,并测试交付和 新的治疗药物的疗效。目标是:1)在以下方面提供专家援助和监督 管理转基因和基因敲除/敲除动物群体,包括它们的基因分型;2)制定 提供动物设施和设备的使用,提供使用指导,并监督 实施动物程序和组织采集;3)提供设备用于开发和 建立眼部疾病和眼部病理性疾病的动物模型;4)为 活体动物成像;5)作为研究人员和大学动物设施之间的联络人 服务。
英文摘要
PROJECT SUMMARY: ANIMAL SERVICES CORE The Animal Services Core is structured to meet the evolving needs of investigators for translational research by providing resources to develop experimental animal models of ocular diseases and test the delivery and efficacy of new therapeutic agents. The goals are: 1) to provide expert assistance and oversight in the management of transgenic and gene knockout/knockin animal colonies, including their genotyping; 2) to make available the use of animal facilities and equipment, provide guidance in their utilization, and supervise the performance of animal procedures and tissue harvesting; 3) to make available equipment for development and generation of animal models of ocular diseases and pathologic eye conditions; 4) to provide assistance in imaging of live animals; 5) to serve as a liaison between investigators and the University's animal facilities and services.
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Functional tomography of neurovascular coupling interactions in healthy and diseased retinas
Functional tomography of neurovascular coupling interactions in healthy and diseased retinas
Super-resolution ophthalmoscopy for in vivo retinal imaging
Functional imaging of retinal photoreceptors
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