Phages Helping Acquire Genuine Experiences in Science (PHAGES)

拟议的项目要求在五年内提供135万美元，以建立 蒙大拿理工学院成功的“吞噬”项目。我们的目标是1)为教师配备 以知识、技能和性格为基础提供高质量的噬菌体 为学生提供研究机会；2)建立可持续的渠道 3)创建自给自足的卫星实验室，以确保 服务不足地区的学生有机会获得当地的研究机会。选择 在课堂上参与噬菌体发现4次或更长时间的教师领导 Year将担任同伴导师，将该项目扩展到他们同事的教室。 1)由K-12学生、教师和本科生组成的多样化人口将 参与发现和鉴定噬菌体的研究工作。拟议中的项目 将整合K-12外展计划，以扩大参与教师队伍和 为数千名K-12学生提供真正的研究体验和严格的测量 该计划的效果。我们假设这个定制的交付和个性化的 辅导将加强留住新加入的教师，增加教师队伍的多样性 参与的学生，并扩大该计划的地理范围。 2)在SEPA和INBRE计划之间的前沿合作中，我们目前 试行一项计划，以拓宽大学预科本科生研究人员的渠道。学生 参与了噬菌体的发现，获得了夏季和学年研究的支持。这 管道将在PHAGES项目期间扩大。在完成高中研究之后 项目，这些新的大学生将过渡到蒙大拿州INBRE支持的项目 蒙大拿州INBRE的八个参与机构，深化他们的研究经验，以及 增加蒙大拿州学生进入生物医学研究的渠道。 3)在PHAGES的支持下，每位教师将发展知识、技能和 以最适合他或她的形式提供课堂噬菌体发现的基础设施 学区，包括建立卫星实验室，用于独立准备 节目的材料和交付。项目成果和开发的材料将是 通过出版物、互联网和在当地、地区和 全国科学、科学和教育会议。就像有100所大学和学院一样 在大学课堂上参与噬菌体发现的教师，这个项目可能会提供一个 将HHMI SEA-PHAGES计划的覆盖范围扩大到K-12教师和学生的模式。

The proposed project requests $1.35 million over five years to build sustainability for the successful “Phagedigging” program at Montana Tech. We aim to 1) equip teachers with the knowledge, skills, and dispositions to provide high-quality bacteriophage-based research opportunities for students; 2) establish a sustainable pipeline for students into the sciences; and 3) create self-sustaining satellite labs to ensure that students in underserved areas have access to local research opportunities. Select teacher leaders who have been involved with phage discovery in their classrooms for 4 or more years will serve as peer mentors to expand the project to their colleagues' classrooms. 1) A diverse population of K-12 students, teachers, and undergraduate students will participate in research efforts to discover and characterize bacteriophages. The proposed project will integrate K-12 outreach programs to broaden the cadre of participating teachers and provide thousands of K-12 students with genuine research experiences and rigorously measure the effects of the program. We hypothesize that this customized delivery and personalized mentoring will enhance retention of newly participating teachers, increase the diversity of participating students, and expand the geographical reach of the program. 2) In a forefront collaboration between SEPA and INBRE programs, we are currently piloting a program to widen the pipeline of precollege undergraduate researchers. Students who participated in phage discovery receive support for summer and academic year research. This pipeline will expand during the PHAGES project. After completing high school research projects, these new college students will transition to Montana INBRE-supported projects at any of eight Montana INBRE participating institutions, deepening their research experiences, and increasing the pipeline of Montana students into biomedical research. 3) With support from PHAGES, each teacher will develop the knowledge, skills, and infrastructure to provide classroom phage discovery in formats most appropriate for his or her school district, including the establishment of satellite labs for independent preparation of materials and delivery of the program. The project results and materials developed will be widely disseminated through publications, internet, and presentations at local, regional, and national science, and science education conferences. As there is >100 universities and college faculty participating in phage discovery in college classrooms, this program may provide a model to expand the reach of the HHMI SEA-PHAGES program to K-12 teachers and students.