Instrument Shop Module

总结/摘要-仪器车间模块 仪器车间模块通过与以下机构密切合作， 来自视觉研究不同科学领域的研究人员设计和构建了独特的， 成功完成NEI支持的手术所需的市售仪器和设备 研究项目。该模块在设计和建造专业仪器方面的专业知识， 设备还有助于促进高素质的研究人员的研究计划， 关于NEI赠款此外，仪器车间模块提供仪器维修服务， 由视觉研究核心的许多参与者，并服务于最大限度地减少NEI资助的视觉中断 research.最后，该模块为功能评估模块和 形态学和成像模块，使这些模块能够满足研究者的特定需求。的 仪器车间模块位于763平方米的英尺在西伦敦的专用空间凯洛格眼科中心， 配备了夏普数控车床、布里奇波特数控铣床、金属加工中心、 立式带锯、Tennsmith直角剪、Tennsmith手刹和Zortrax M200 3D 打印机为了帮助仪器设计并提高制造过程的效率，该模块利用 SolidWorks CAD系统。该模块的全职仪器制造商设计和制造机械 仪器，如显微操作器、平移台、加热系统、显微镜适配器、光 来源和环境控制的动物住房箱。此外，许多独特的专业 用树脂玻璃创建项目（例如，斑马鱼和小鼠定位设备和灌注 用于执行电生理记录和成像的腔室）。在上一个供资期间， 6名参与研究者广泛使用仪器车间模块，另外4名中度使用 用户.在下一个资助期内，9名参与研究者预计将使用该模块， 广泛程度。

SUMMARY/ABSTRACT - Instrument Shop Module The Instrument Shop Module significantly enhances the research environment by working closely with investigators from disparate scientific areas of vision research to design and construct unique, non- commercially available, instruments and devices that are required to successfully complete NEI-supported research projects. The Module's expertise in the design and construction of specialized instruments and devices also serves to facilitate the research programs of highly qualified investigators preparing to become PIs on NEI grants. In addition, the Instrument Shop Module provides an instrument repair service that is used by many participants of the Vision Research Core and serves to minimize disruptions in NEI-funded vision research. Finally, the Module constructs unique devices for the Functional Assessment Module and the Morphology and Imaging Module, which allows these Modules to meet the specific needs of investigators. The Instrument Shop Module is housed in 763 sq. ft. of dedicated space in the W.K. Kellogg Eye Center and is equipped with a Sharp CNC (computer numerical control) lathe, a Bridgeport CNC milling machine, a metal vertical band saw, a Tennsmith squaring shear, a Tennsmith hand brake, and access to a Zortrax M200 3D printer. To aid in instrument design and to increase efficiency in fabrication processes, the Module utilizes the SolidWorks CAD system. The Module's full-time Instrument Maker designs and fabricates mechanical instruments such as micromanipulators, translation stages, heating systems, microscope adapters, light sources and environmentally-controlled animal housing boxes. In addition, numerous uniquely specialized items are created with Plexiglas (for example, zebrafish and mouse positioning devices and perfusion chambers for performing electrophysiological recordings and imaging). During the prior funding period, the Instrument Shop Module was extensively utilized by 6 participating investigators with another 4 being moderate users. In the next funding period, 9 participating investigators anticipate using the Module to a moderate or extensive degree.