Mays Cancer Center at UT Health SA

项目摘要-光学成像共享资源 光学成像共享资源(OISR)的任务是提供最先进的光学成像 给梅斯癌症中心(MCC)和圣安东尼奥大学健康学院成员的方法学 (UT Health SA)。OISR自1999年开始运作，当时它首次被列为癌症中心- 支持的共享资源。OISR总面积为2400平方英尺。英国《金融时报》位于校园内两个地点的空间，一个 1000平方英尺设施位于主校区的牙科学校大楼内，占地1,400平方英尺。位于南得克萨斯州的工厂 格里希校区的研究设施大楼(STRF)。这一最先进的设施由与 癌症中心和德克萨斯大学健康管理局。OISR拥有广泛的现代光学成像系统 为了满足癌症研究所需的各种生物医学体外和体内应用的需求，从 单分子到整个动物，从培养细胞到深层组织，包括高时间分辨率 快速事件的活细胞成像。我们的系统包括共焦/多光子显微镜、广域显微镜、 荧光寿命成像显微镜、荧光光谱成像、超分辨率、光片 显微镜和整个动物的成像。服务包括一对一、动手培训和协助 仪器操作和图像分析，获得最先进的光学成像仪器，咨询 关于实验设计和样品制备，以及资助申请的支持函。酒店里的员工 OISR成员：James Lechleiter博士(主任)、Exing Wang博士(联席主任)和Jimmy Wewer (影像技术员)。在最近的获奖年，21名癌症中心成员使用了OISR 同行评审的资金，占共享资源用户总数的27%。

Project Summary—Optical Imaging Shared Resource The mission of the Optical Imaging Shared Resource (OISR) is to provide state-of-the-art optical imaging methodologies to members of the Mays Cancer Center (MCC) and the University of Texas Health San Antonio (UT Health SA). The OISR has been in operation since 1999, when it was first included as a Cancer Center- supported Shared Resource. The OISR has a total of 2,400 sq. ft. of space located in two sites on campus, a 1,000 sq.ft. facility in the Dental School building on the main campus and a 1,400 sq.ft. facility in the South Texas Research Facility Building (STRF) on the Greehey Campus. This state-of-the-art facility is managed jointly with the Cancer Center and the UT Health SA. The OISR houses a wide spectrum of modern optical imaging systems to meet the demands for various biomedical in vitro and in vivo applications needed for cancer research, from single molecules to whole animals and from cultured cells to deep tissue, including high temporal resolution for live cell imaging of rapid events. Our systems include confocal/multiphoton microscopy, widefield microscopy, fluorescence lifetime imaging microscopy, fluorescence spectral imaging, super resolution, light sheet microscopy, and whole animal imaging. Services include one-on-one, hands-on training and assistance with instrument operation and image analysis, access to state-of-the-art optical imaging instrumentation, consultation on experimental design and sample preparation, and supporting letters for grant applications. The staff in the OISR include: James Lechleiter, Ph.D. (Director), Exing Wang, Ph.D. (Co-Director), and Jimmy Wewer (Imaging Technologist). In the most recent award year, the OISR was used by 21 Cancer Center members with peer-reviewed funding, which comprises 27% of the total Shared Resource users.