DCEG- Genotyping for epidemiology studies

癌症基因组学研究（CGR）实验室的建立是为了研究遗传变异对癌症易感性和结果的贡献。与流行病学家，生物统计学家和基础研究科学家在DCEG的校内研究计划合作，CGR提供了进行全基因组发现研究和有针对性的区域方法的能力，以确定各种形式的癌症的遗传决定因素。 新的工作已经开始在体细胞研究中使用肿瘤/正常组织核酸进行跨平台比较感兴趣的主题。 CGR内的分子和数字病理学研究的支持小组已经增加，以支持这些努力。 CGR在癌症研究的所有阶段为DCEG提供支持，从规划到出版，包括实验设计和项目管理，样品处理，基因分型和测序检测设计和执行，组织研究支持，生物信息学管道的开发和实施，以及下游研究和分析支持。 这些因素使CGR成为NCI驱动的科学努力的独特合作中心。

The Cancer Genomics Research (CGR) Laboratory was established to investigate the contribution of genetic variation to cancer susceptibility and outcomes. Working in concert with epidemiologists, biostatisticians, and basic research scientists in DCEG’s intramural research program, the CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer. New work has begun in somatic research with the use of tumor/normal tissue nucleic acids for cross-platform comparisons in subjects of interest. A support group for molecular and digital pathology research within CGR has been added to support these efforts. CGR supports DCEG in all stages of cancer research from planning to publishing, including experimental design and project management, sample handling, genotyping and sequencing assay design and execution, tissue research support, development and implementation of bioinformatic pipelines, and downstream research and analytical support. These factors make CGR a unique collaborative center for NCI-driven scientific endeavors.