RAS Program at FNL

RAS项目是一项有针对性的计划，旨在开发针对由异常RAS信号驱动的癌症的治疗策略，特别是RAS基因突变的结果，由弗雷德里克国家癌症研究实验室（FNLCR）主持，该实验室是卫生和人类服务部唯一由联邦政府资助的研究与发展中心（FFRDC）。按照设想，该项目将是一个中心和辐条模式，科学领袖、核心设施和重要技术在FNLCR中心，研究由公司、学术机构和NCI内部研究项目的研究人员领导。2014财年有五个项目正在开发中，以这些癌症为目标。这笔开支用于购置基本设备，以便在本研究所进行实验室研究。

The RAS Program is a targeted plan to develop therapeutic strategies against cancers driven by abnormal RAS signaling, especially as a consequence of RAS gene mutations, under the auspices of the Frederick National Laboratory for Cancer Research (FNLCR), the only Federally Funded Research and Development Center (FFRDC) in the Department of Health and Human Services. It is envisioned that the program will be a hub and spoke model, with scientific leaders, core facilities and important technologies at the FNLCR hub, and research led by investigators at companies, academic institutions and the NCI intramural research program at the spokes. There are five projects currently under development in FY14 to target these cancers. This expenditure is for the purpose of capital equipment to carry out laboratory research at FNLCR.