PDX Core

项目摘要- PDX核心 PDX核心为项目研究者提供主要资源，包括黑色素瘤PDX、黑色素瘤 细胞系和3D模型来探索新的疗法。黑色素瘤PDX包括>450种不同的肿瘤 代表疾病的所有临床和遗传组。PDX核心的主要重点是建立 新的PDX，并协调其在DNA，RNA和蛋白质水平的表征。然后，它维护 主细胞库，监测小鼠病原体，并与项目内的其他研究人员合作， 在整个PDTC和外部科学家。核心也是在内部交换PDX的中央促进者。 PDXNet用于协调合作。核心协调数据存储和分发， 项目内的其他研究人员。 PDX核心可用于培训该计划的研究人员进行所有生物测定和模型。总的来说， 该核心将为PDTC内的所有实验室提供高效和高质量的服务。 1

Project Summary – PDX Core The PDX Core provides major resources to the program investigators, including melanoma PDX, melanoma cell lines and 3D models to explore new therapies. The melanoma PDX encompasses >450 different tumors representing all clinical and genetic groups of the disease. The primary focus of the PDX core is to establish new PDX and coordinate their characterization at the DNA, RNA, and protein levels. It then maintains the master cell bank, monitors for mouse pathogens, and collaborates with other investigators within the program, within the overall PDTC and outside scientists. The Core is also to central facilitator for exchanging PDX within the PDXNet for a coordinated effort on collaborations. The Core coordinates data storage and distribution to other investigators within the Program. The PDX Core is available to train investigators of the Program in all biological assays and models. Overall, this Core will provide efficient and high-quality service to all laboratories within this PDTC. 1