Mass Spectrometry Identification

质谱研究和支持小组已经或正在进行蛋白质鉴定方面的各种服务和合作项目，分析了来自8个实验室分支和DNTP的21名主要研究人员或核心负责人的33名科学家的约5000个样品。 一个大的努力是支持结构生物学核心实验室和鲍勃彼得罗维奇博士的蛋白质表达功能。MSRSG的作用是在结构生物学核心实验室将材料移交给其用户之前，在蛋白质水平上确认基因表达。 其他尚未公布的项目仍在进行中，包括： MALDI-MS鉴定细菌病原体大卫库尔茨 NTHL 1（Doetsch）; Rubicon（Martinez）; Grc 3/Las 1（Stanley）; TSEN（Stanley）; SMCHD 1（Shaw）;未表征酯酶（威廉姆斯）; VRK 1（Negishi）结合配偶体的鉴定 其他项目集中在识别与RNA元件相互作用的蛋白质（Hall）。 额外的项目，需要超过可以忽略不计的资源，包括与黑剪，费斯勒，哈利，R。伦敦和胡实验室。

A variety of service and collaborative projects in protein identification have been or are being carried out within the Mass Spectrometry Research and Support Group with approximately 5000 samples analyzed from 33 scientists representing 21 principal investigators or core heads from 8 laboratory branches and the DNTP. One large effort is in support of the protein expression function of the Structural Biology Core Laboratory and Dr. Bob Petrovich. The Role of the MSRSG is to confirm gene expression at the protein level prior to the Structural Biology Core Laboratory handing materials over to their users. Other unpublished projects that are still ongoing include: Identification of bacterial pathogens by MALDI-MS David Kurtz Identification of binding partners of NTHL1 (Doetsch); Rubicon (Martinez); Grc3/Las1 (Stanley); TSEN (Stanley); SMCHD1 (Shaw); uncharacterized esterase (Williams); VRK1 (Negishi) Additional projects focused on the identification of proteins that interacted with RNA elements (Hall). Additional projects that have required more than negligible resources include efforts performed with the Blackshear, Fessler, Harry, R. London, and Hu laboratories.