New and improved treatment strategies for neonatal seizures

澳大利亚每年约有10%的新生儿被诊断为癫痫发作。缺氧性脑损伤后癫痫发作恶化神经发育结果。尽管有证据表明目前抗癫痫药物的有效性和潜在的神经毒性有限，但几十年来治疗方法一直没有改变。这项研究的目的是优化新生儿癫痫发作的治疗，这种化合物是有效的，不会造成伤害，或者确实为受损的大脑提供神经保护。

Around 10% of neonates in Australia are diagnosed with seizures each year. Seizures worsen neurodevelopmental outcome following hypoxic brain injury. Despite evidence of the limited effectiveness and potential neurotoxicity of current anti-seizure medication, treatment has not changed for many decades. The objective of this study is to optimise treatment of neonatal seizures with a compound that is effective and does not cause harm, or indeed provides neuroprotection for the compromised brain.