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中文摘要
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项目摘要 小鼠提供了一个强大的遗传模型系统,因此是神经科学中唯一最常用的动物模型。尽管 无线记录的潜在好处(更灵活、更安全、更自然的活体神经记录),采用 在神经科学界,小鼠对更广泛的神经科学界的无线记录一直很慢,原因是 使轻量级设备能够记录/传输高保真/多通道/高带宽信号的工程复杂性 合理的录制时间。市场上的无线神经记录设备目前要么基于模拟 传输,用低计数/低通道换取更长的时间,对老鼠来说太重,或者仍然太贵。无人提供 同时记录和电刺激高声道,完全集成到行为软件中,非常适合 老鼠还没来。 京和喜公司的S Jaga Penny(作为最终产品)将作为紧凑型(硬币大小的一体式)在市场上独一无二, 价格实惠(5.5-7.5K美元)、高质量、能够同时记录神经的多通道无线系统(高达32路) 以及对小鼠的高频信号(单元记录)和低波段信号的刺激(高达16/32ch)。此外, 我们易于使用且可扩展(同时支持4-8台设备)的系统将完全集成到现有的领先产品中 市场上的行为和视频/事件跟踪软件。我们预计Jaga Penny将广泛协助 神经科学家在更自然的活体环境中将电生理学和行为实验结合起来的努力。
英文摘要
Project Summary Mice offer a powerful genetic model system, thus are the single most used animal model in neuroscience. Despite potential benefits of wireless recording (more flexible, safer, and more natural in vivo neural recording), adoption of wireless recording in the neuroscience community for mice for a wider neuroscience community had been slow, due to the engineering complexity to enable a lightweight device record/transmit high fidelity/multichannel/high bandwidth signals for reasonable recording hours. Wireless neuro recording devices on the market are currently either analog based transmission, trade low count/low channel for longer hours, too heavy for mice or still too expensive. None provide simultaneous recording and electrical stimulation for high channels with full integration into behavioral software ideal for mice yet. Jinga-hi, Inc.'s JAGA Penny (as a final product) will be unique on the market as a compact (coin-sized all in one), affordable ($5.5-7.5K), high quality, multichannel wireless system capable of simultaneous neural recording (up to 32 ch) and stimulation (up to 16/32 ch) for high band signals (unit recording) as well as low band signals for mice. In addition, our easy to use and scalable (4-8 devices at the same time) system will be fully integrated into available leading behavioral and video/event-tracking software on the market. We anticipate that JAGA Penny will widely assist neuroscientists' efforts in combining electrophysiology and behavior experiments in a more natural in vivo environment.
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Affordable wireless neural recording for mice
  • 批准号:
    9138954
  • 项目类别:
  • 资助金额:
    $22.02万
  • 财政年份:
    2016
  • 负责人:
    Mee H Choi
  • 依托单位:
Autophosphorylation of CaMKII in Neural Signal Transduction
Autophosphorylation of CaMKII in Neural Signal Transduction
Autophosphorylation of CaMKII in Neural Signal Transduction
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