Optimizing Implementation in Cancer Control: OPTICC

总体汇总 OPTICC（优化癌症控制实施）中心的使命是改善癌症预后 通过支持癌症控制中循证干预措施（EBI）的优化实施。优化 实施发生在：（1）用于实施EBI的战略解决了以下关键障碍： （2）在实施的具体环境中积极实施的战略，以及（2）这些战略 反映解决障碍的最佳可能方法。尽管在实施方面取得了二十年的进展， 科学（IS），实用工具和指导，以支持优化的EBI实施缺乏;因此， 战略往往与障碍不匹配，而且往往没有针对有效性、效率进行优化，也不适合当地 资源其结果是以时间、精力和资源损失的形式出现的次优实施，最终， 癌症预后较差。OPTICC中心将推进IS，进而改善EBI在癌症中的实施 通过开发、测试和改进优化EBI实施的创新方法来控制。关于OPTICC 该中心是华盛顿大学（UW）、Kaiser Permanente华盛顿健康中心（Kaiser Permanente Health） 研究所（KPWHRI）和弗雷德哈钦森癌症研究中心（FHCRC）。三个核心将 支持其工作。行政核心将促进多学科合作，卓越的研究， 方法创新。它还将领导中心的外联和传播工作，评估中心的影响， 协调中心活动。研究计划核心将进行创新的实施研究，方法 和测量研究，以及小型试点研究，推进中心的“大挑战”是主题， 优化EBI实施。将采用一种三阶段方法来优化EBI的实施， 并对障碍、匹配策略和测试策略进行优先级排序--测量开发涵盖所有这三个方面 阶段实施实验室核心将建立和协调一个网络， 社区网站进行“体内”IS研究，实施癌症控制EBI，并塑造中心的研究 施政纲要的演讲该中心的初步研究将侧重于优化宫颈癌筛查EBI的实施， 结肠直肠癌乳腺癌和卵巢癌然而，优化EBI实施的方法， 将开发，测试和完善可以广泛应用于整个癌症护理连续体，为广泛的癌症， 来回答一系列的问题

OVERALL SUMMARY The mission of the OPTICC (Optimizing Implementation in Cancer Control) Center is to improve cancer outcomes by supporting optimized implementation of evidence-based interventions (EBIs) in cancer control. Optimized implementation occurs when: (1) the strategies employed to implement EBIs address the key barriers to implementation that are active in the specific settings in which implementation occurs, and (2) those strategies reflect the best possible methods for addressing the barriers. Despite two decades of progress in implementation science (IS), practical tools and guidance to support optimized EBI implementation are lacking; as a result, strategies are often mismatched to barriers and are often not optimized for effectiveness, efficiency, or fit with local resources. The result is suboptimal implementation in the form of lost time, effort, and resources and, ultimately, poorer cancer outcomes. The OPTICC Center will advance IS and, in turn, improve EBI implementation in cancer control by developing, testing, and refining innovative methods for optimizing EBI implementation. The OPTICC Center is a strategic collaboration of the University of Washington (UW), Kaiser Permanente Washington Health Research Institute (KPWHRI), and the Fred Hutchinson Cancer Research Center (FHCRC). Three cores will support its work. The Administrative Core will promote multidisciplinary collaboration, research excellence, and methodological innovation. It will also lead Center outreach and dissemination efforts, evaluate Center impact, and coordinate Center activities. The Research Program Core will conduct innovative implementation studies, method and measurement studies, and small pilot studies that advance the Center’s “grand challenge” IS theme of optimizing EBI implementation. A three-stage approach to optimizing EBI implementation will be taken—identify and prioritize barriers, match strategies, and test strategies—with measurement development spanning all three stages. The Implementation Laboratory Core will establish and coordinate a network of diverse clinical and community sites to conduct “in vivo” IS studies, implement cancer control EBIs, and shape the Center’s research agenda. The Center’s initial studies will focus on optimizing implementation of screening EBIs for cervical, colorectal, breast, and ovarian cancer. However, the methods for optimizing EBI implementation that the Center will develop, test, and refine can be applied broadly across the cancer care continuum, for a wide range of cancers, to answer a wide range of IS questions.