Mentoring and research in mind-body and integrative therapies

这是为彼得·韦恩博士设立的面向患者研究(POR)的K24职业中期研究员奖， 奥舍综合医学中心(哈佛医学院联合研究中心)研究主任 和布里格姆妇女医院(BWH))，以及HMS医学助理教授(晋升为 (候任副教授)。在过去的15年里，韦恩博士成功地建立了一个持续资助的 研究计划侧重于评估多种综合医学(IM)疗法的临床影响， 包括太极、针灸和手法疗法，用于预防和康复广泛的 慢性健康状况。借鉴早期研究生涯中的多种实验和分析技能 在进化生物学方面，以及作为综合疗法实践者和教师的重要临床经验， 他已经发展了必要的知识和技能来进行高质量的POR并在这方面指导其他人 进程。在这个K24奖项中提出的一套协调的倡议将为韦恩博士提供所需的 保护时间以显著：1)扩大他对初级调查员的指导的数量和质量 致力于IM研究；以及2)提高他的研究技能，扩大他的研究组合作为 为未来指导IM疗法和模型的使用提供信息的创新和高影响研究奠定基础。 加强他的指导的举措包括：参加波士顿大学教师领导力培训计划； 制定更有结构和更全面的指导计划，以适应个人水平的需要 受训人员；与一个由忠诚的高级教职顾问组成的团队定期举行会议；以及减少 用于行政活动的时间，这些时间将重新分配给指导。这些倡议的成功 韦恩博士目前在奥舍中心的领导角色将得到加强；可以接触到丰富的导师池 通过他担任教员的两个长期由NIH资助的T32奖学金的候选人，以及 与奥舍中心合作的多个其他地方、国家和国际培训和研究项目 合作；以及HMS医院和机构提供的丰富教育资源，包括 哈佛催化剂，美国国立卫生研究院资助的临床和翻译科学奖网站。韦恩博士目前的研究 该计划是高度协作的，包括两个NIH R01，他在这两个R01中担任多重PI，另外两个 他作为PI领导的基金会资助的研究，以及他作为关键合作者的其他6项研究。 这些研究以及有待开发的未来研究都以研究策略为中心进行了总结 围绕三个全球目标：1)评估慢性下腰痛的综合医学方法；2)进行 评价太极拳康复效果和成本效益的翻译研究 预防慢性病相关功能衰退；3)评价太极运动对认知功能和运动功能的影响 帕金森氏病的运动过程。总体而言，当前和未来计划的研究将提供一个 多元化、创造性、资金充足和支持性的研究环境，以培训初级IM调查人员。

This is a proposed K24 Mid-Career Investigator Award in Patient-Orient Research (POR) for Dr. Peter Wayne, Director of Research at Osher Center for Integrative Medicine (jointly based at Harvard Medical School (HMS) and Brigham and Women's Hospital (BWH)), and Assistant Professor in Medicine at HMS (promotion to Associate Professor pending). Over the past 15 years, Dr. Wayne has built a successful, continuously funded, program of research focused on evaluating the clinical impact of multiple integrative medicine (IM) therapies, including Tai Chi, acupuncture, and manual therapies, for the prevention and rehabilitation of a broad range of chronic health conditions. Drawing on multiple experimental and analytic skills from an earlier research career in evolutionary biology, and significant clinical experience as a practitioner and teacher of integrative therapies, he has developed the knowledge and skills necessary to conduct high quality POR and to guide others in this process. The coordinated set of initiatives proposed in this K24 award will provide Dr. Wayne with needed protected time to significantly: 1) expand the quantity and quality of his mentoring of junior investigators committed to IM research; and 2) increase his research skills and expand his portfolio of research as a foundation for leading future innovative and high impact studies informing the use of IM therapies and models. Initiatives to enhance his mentoring include: Participation in the BWH faculty leadership training program; development of a more structured and comprehensive mentoring plan that is tailored to the individual level of the trainees; regular meetings with an assembled team of committed senior faculty advisors; and reduction in time devoted to administrative activities which will be reallocated to mentoring. The success of these initiatives will be augmented by Dr. Wayne's current leadership role at the Osher Center; access to a rich pool of mentee candidates via two long-standing NIH-funded T32 Fellowships for which he serves as faculty, as well as multiple other local, national, and international training and research programs with which the Osher Center collaborates; and the rich educational resources afforded across HMS hospitals and institutions, including the Harvard Catalyst, an NIH-funded Clinical and Translational Science Award site. Dr. Wayne's current research program is highly collaborative, and includes two NIH R01s for which he serves as a multiple PI, two additional foundation-funded studies that he leads as PI, and 6 other studies for which he serves as a key collaborator. These studies, along with future studies to be developed, are summarized in a Research Strategy centered around three global aims: 1) to evaluate integrative medical approaches to chronic low back pain; 2) to conduct translational research evaluating the effectiveness and cost-effectiveness of Tai Chi for rehabilitation and prevention of chronic disease related functional decline; 3) to evaluate the impact of Tai Chi on cognitive and motor processes in Parkinson's disease. Collectively, current and future planned studies would provide a diverse, creative, well-funded, and supportive research environment to train junior IM investigators.