Pathology Core

摘要：病理学核心 在马拉维，组织诊断对于癌症护理和研究以及应对与艾滋病毒相关的恶性肿瘤至关重要 南非将严重依赖于确保可靠地获得强大的病理服务。 实现这一目标需要人力和物力资源的战略性和多学科协调 随着时间的推移，以及跨地理地点和科学项目的诊断病理学。这是一个困难的问题 即使在高收入国家也是如此，后勤挑战在低收入国家和 中等收入国家。改善SSA癌症护理和研究的举措需要准确、成本- 有效的、数据驱动的组织采集和诊断方法，以及强大的区域病理学 网络是最终改善患者结局和进行有影响力的研究的重要基础。 认识到这一点，UNC-马拉维-南非癌症联盟(UMSACC)将建立一个共享的- 资源病理学核心。核心将由来自北卡罗来纳大学教堂山、北卡罗来纳大学马拉维项目的调查人员组成 马拉维的卡穆祖中心医院、南非的威特沃特斯兰德大学和斯泰伦博什 南非的大学。病理学核心将提供先进和全面的诊断支持 本提案中的多机构研究项目通过开展中央病理学审查 进程，在特定疾病领域内建立工作组，积极确定区域最佳做法，以及 培养下一代病理学家。

ABSTRACT: PATHOLOGY CORE Tissue diagnosis is essential for cancer care and research, and addressing HIV-related malignancies in Malawi and South Africa will be critically dependent on ensuring reliable access to robust pathology services. Achieving this requires strategic and multidisciplinary coordination of human and material resources for diagnostic pathology over time, as well as across geographic sites and scientific projects. This is a difficult undertaking even in high-income countries, and logistical challenges are significantly amplified in low- and middle-income countries. Initiatives to improve cancer care and research in SSA require accurate, cost- effective, and data-driven approaches to tissue acquisition and diagnosis, and strong regional pathology networks are an essential foundation to ultimately improve patient outcomes and conduct impactful research. Recognizing this, the UNC-Malawi-South Africa Cancer Consortium (UMSACC) will establish a shared- resource Pathology Core. The core will comprise of investigators from UNC Chapel Hill, UNC Project-Malawi and Kamuzu Central Hospital in Malawi, the University of the Witwatersrand, South Africa and Stellenbosch University, South Africa. The Pathology core will provide advanced and comprehensive diagnostic support to the multi-institutional research projects in this proposal through development of a central pathology review process, establish working groups within specific disease areas to actively identify regional best practices, and train the next generation of pathologists.