Core A: Administrative Core

行政核心--项目摘要/摘要 行政核心设在血液研究所(BRI)的行政办公室内， Versiti的研究部门(f/k/a威斯康星州血液中心)。核心A是管理和临床数据 协调PPG及其所有组件的核心工作。这个PPG包括世界上最杰出的科学家 Versiti的BRI以及弗吉尼亚州的里士满和纽约州的布法罗，它们都密切关注多糖的生物学 以及导致骨髓增生性疾病的机制。行政核心将提供协调的、 为方案参与者提供集中支持，包括项目负责人和核心主管。目标1 为项目负责人和核心主任提供行政协调和科学领导，并 处理与美国国立卫生研究院的所有财务和行政协调。目标2核心A将安排定期(每月) 项目负责人和核心主管之间的会议视频会议、正在进行的研究会议、面对面 在Versiti BRI、弗吉尼亚联邦大学或罗斯威尔公园癌症研究所举行的会议，以及 协调“五大湖翻译糖篇研讨会”系列活动。目标3是提供一个中心站点来 管理已确认身份的人体样本和获取的数据的在线数据库。这些管理职能 将在首席调查员的直接监督下进行，首席调查员也是 Versiti‘s BRI的翻译血糖中心。

Administrative Core - Project Summary/Abstract The Administrative Core is located within the administrative offices of the Blood Research Institute (BRI), the research arm of Versiti (f/k/a BloodCenter of Wisconsin). Core A is the Administrative and Clinical Data Coordinating Core for the PPG and all of its components. This PPG includes outstanding scientists within the Versiti's BRI and in Richmond, Virginia and Buffalo, New York that are tightly focused on the biology of glycans in blood and mechanisms causing myeloproliferative disease. The Administrative Core will provide coordinated, centralized support for the participants of the Program, including the Project Leaders and Core Directors. Aim 1 is to provide administrative coordination and scientific leadership to the Project Leaders and Core Directors and handle all fiscal and administrative coordination with NIH. Aim 2 Core A will schedule the periodic (monthly) conference video calls between Project Leaders and Core Directors, research in progress meetings, in-person meetings held at the Versiti BRI, Virginia Commonwealth University, or Roswell Park Cancer Institute and to coordinate the “Great Lakes Translational Glycomics Symposium” Series. Aim 3 is to provide a central site to manage an online database of de-identified human samples and acquired data. These administrative functions will be carried out under the direct supervision of the Principal Investigator, who is also Director of the Translational Glycomics Center at Versiti's BRI.