Expanding Opportunities in Genomic Research for Underrepresented Students

翻译后摘要：这项建议寻求更新的机会，基因组学研究（OGR）计划。以来 2007年，OGR计划由位于圣路易斯的华盛顿大学麦克唐纳基因组研究所运行。 路易斯和资助通过NHGRI的多样性行动计划。OGR计划的使命是增加 来自基因组科学或基因组科学相关博士学位代表性不足群体的学生的代表性 MD/PhD课程我们寻求通过有效执行和发展以下方面来完成我们的使命： 夏季本科和学年后学士学位研究计划的学生从种族和 在科学中代表性不足的种族背景，来自弱势背景的学生，以及 残疾人。两个OGR项目都为学员提供基因组科学的前沿研究经验 或相关领域和11个其他教育活动，旨在培养他们批判性思考和写作， 有效地谈论他们的研究。研讨会和课程是为培养学生的核心概念而量身定制的 基因组科学、生物信息学和科学报告。专业发展活动的重点是 帮助学生准备并在研究生院面试和研究生院本身中脱颖而出。 在三个资助周期中，OGR计划的学生成果显示出巨大的势头。博士 我们暑期课程的学生入学率从第一周期的29%上升到最后两个周期的50%或以上 自行车.更令人印象深刻的是，在我们的学士后课程中，博士生入学率从2004年的44%上升到2006年的44%。 第一个周期为75%，第二个周期为90%。我们期待新的 并修改活动以巩固和扩大这些成果。具体而言，新活动将促进融合 在OGR学员和NHGRI T32博士基因组科学计划的学员中，加强以下方面的培训： 生物信息学，为学员提供更多的接触研究职业的多样性，以博士 科学家，并发起社区外展活动，以服务不足的地区高中及其学生。 根据我们过去的成功和目前的计划，我们寻求五年以上的资金支持， 继续我们的使命，提高博士课程的多样性全国。我们建议扩大我们的职位- 学士学位计划，每年五名学员，并与大学的支持，以保持我们的夏季规模 本科课程，每年夏季8名学生。我们相信我们的计划将继续帮助实现 巨大的科学和智力潜力固有的不同人口的美国，大部分 由于我国人口中许多部门的代表性不足， 一般的科学研究，特别是基因组科学。

Abstract: This proposal seeks the renewal of the Opportunities in Genomics Research (OGR) Program. Since 2007, the OGR Program has been run out of The McDonnell Genome Institute at Washington University in Saint Louis and funded through the NHGRI's Diversity Action Plan. The mission of the OGR Program is to increase the representation of students from underrepresented groups in genome science or genome science-related PhD and MD/PhD programs. We seek to accomplish our mission through the effective execution and evolution of summer undergraduate and academic year post-baccalaureate research programs for students from racial and ethnic backgrounds underrepresented in the sciences, students from disadvantaged backgrounds, and students with disabilities. Both OGR programs provide trainees with cutting-edge research experiences in genome science or related fields and 11 other educational activities that seek to train them to think critically and to write and speak effectively about their research. Workshops and classes are tailored to train students in the core concepts of genome science, bioinformatics, and scientific presentation. Professional development activities focus on helping students prepare for and excel in graduate school interviews and graduate school itself. Over its three funding cycles, student outcomes for the OGR program reveal great momentum. PhD matriculation of students in our summer program rose from 29% in the first cycle to 50% or above the last two cycles. More impressively, PhD matriculation of students in our post-baccalaureate program rose from 44% in the first cycle to 75% in the second cycle and 90% in the current cycle. We expect the implementation of new and modified activities to solidify and extend these gains. Specifically, new activities will promote integration among OGR trainees and trainees in the NHGRI T32 PhD Genomic Sciences program, enhance training in bioinformatics, provide trainees with greater exposure to the diversity of research careers available to PhD scientists, and initiate community outreach events to under-served area high schools and their students. Based on the past success and current plans of our program, we seek support for five more years of funding to continue our mission of enhancing diversity in PhD programs nation-wide. We propose to expand our post- baccalaureate program to five trainees per year, and with university support, to maintain the size of our summer undergraduate program at eight students per summer. We believe our programs will continue to help realize the great scientific and intellectual potential inherent within the diverse population of the United States, much of which currently lies latent due to the underrepresentation of many sectors of our nation's population within scientific research in general and genome science in particular.