SBU Chemistry-Biology Interface Training Program

描述（由申请人提供）：该提案要求为斯托尼布鲁克大学（SBU）的博士前化学生物学培训计划提供资金。这个跨学科和跨部门的计划为博士提供化学生物学培训机会。学生从四个参与单位中选出：生物化学与结构生物学，化学，分子遗传学与微生物学，分子与细胞药理学研究生课程。参与教师导师（29）在传染病，癌症和毒理学，免疫学，发育生物学，能量收集，细胞信号，有机合成，物理有机化学，酶学和材料化学的研究兴趣。受训人员接受化学和生物学原理和技术的教育，具有核心跨学科的三学期化学生物学课程序列。所有学员和导师参加化学生物学和药物发现研究所年度研讨会和海报会议。这个务虚会是一个途径，通过它培养学生和教师之间的广泛互动和学员群体保持一个有凝聚力的身份。学生们在学年期间每月与项目总监或导师共进午餐一次，作为职业反馈，项目评估和双向反馈的论坛。学员参加他们的家庭研究生课程研究俱乐部和系列研讨会，以扩大他们的知识和网络机会超越培训计划。在他们的第四年，学员与新闻学院合作，将他们以前准备的研究谈话转换为非科学家可以理解和欣赏的演讲，最引人注目的是在社区外展论坛上展示。学员邀请外部研讨会发言人。主要通过参加“科学诚信”课程来进行负责任的研究行为的教学。通过SBU AGEP夏季本科生研究计划和广泛的推广活动，实现了代表性不足群体的招聘。参加CBI培训方案的导师人数为29人，第一年要求提供4个供资职位，随后几年要求提供8个供资职位。 公共卫生相关性：研究生的培训是必不可少的，现在和未来的发现，在生物医学研究，从癌症化疗到新的抗感染药物。该培训计划将为学生提供化学方法和生物方法的培训，这对于开发新的和更好的疾病诊断和治疗方法是必要的。

DESCRIPTION (provided by applicant): This proposal requests funding for the predoctoral Chemical Biology Training Program at Stony Brook University (SBU). This interdisciplinary and interdepartmental Program offers chemical biology training opportunities for Ph.D. students selected from four participating units: the Biochemistry & Structural Biology, the Chemistry, the Molecular Genetics & Microbiology, and the Molecular & Cellular Pharmacology graduate programs. Participating faculty mentors (29) have research interests in infectious disease, cancer and toxicology, immunology, developmental biology, energy-harvesting, cell-signaling, organic synthesis, physical organic chemistry, enzymology, and materials chemistry. Trainees are educated in the principles and techniques of both chemistry and biology with a core interdisciplinary three-semester Chemical Biology course sequence. All trainees and mentors participate in the Institute of Chemical Biology and Drug Discovery annual symposium and poster session. This retreat is one avenue by which extensive interactions between students and faculty are fostered and the trainee group maintains a cohesive identity. The students meet for lunch with a Program Director or Mentor once per month during the academic year as a forum for feedback on careers, program assessment and two-way feedback. Trainees participate in their home graduate program research clubs and seminar series to broaden their knowledge and networking opportunities beyond the training program. In their fourth year, trainees work with Journalism faculty to convert their previously prepared research talks to presentations that non-scientists can understand and appreciate with the most compelling to be presented in a community outreach forum. Trainees invite outside seminar speakers. Instruction in the responsible conduct of research is carried out primarily through participation the course, "Scientific Integrity". Recruitment of underrepresented groups is achieved through the SBU AGEP summer undergraduate research programs and extensive outreach. The number of mentors participating in the CBI Training Program is 29 and four funded positions are requested in the first year and eight funded positions are requested in subsequent years. PUBLIC HEALTH RELEVANCE: Training of graduate students is essential for present and future discovery in biomedical research spanning cancer chemotherapy to new anti-infectives. This training program will provide students with training in chemical methods and biological methods that is necessary for developing new and better diagnostics and treatments for disease.