AIDS International Training and Research Program

描述(由申请者提供)：本提案请求支持威尔康奈尔医学院(WMC或康奈尔大学)继续培训海地科学家在艾滋病毒和相关机会性感染方面的生物医学、流行病学、实验室、临床、操作、卫生服务和行为研究方面的表现。该项目的总部设在康奈尔大学国际医学和传染病部门，有一个跨学科的调查小组，他们与海地有广泛的合作。与范德比尔特大学、哈佛大学、加州大学(伯克利分校)、黑斯廷斯中心和亚伦·戴蒙德艾滋病研究中心加强合作，提供多样化的培训机会。该计划将继续强调在海地的中长期高级研究培训。自成立以来，AITRP项目已为121名海地生物医学人员提供了中长期培训，目前98%的人员在海地从事艾滋病毒/艾滋病工作。提供的培训将涉及六个艾滋病毒/艾滋病研究类别：1)艾滋病毒疫苗试验；2)抗逆转录病毒临床试验；3)儿科和母婴传播研究；4)与艾滋病毒相关的机会性感染--结核病和人乳头瘤病毒感染(HPV)；5)伦理和行为研究，重点是青少年；以及7)发病机制、免疫学和病毒学。拟议的培训将主要在海地进行，大部分培训由前Fogarty学员完成。该培训计划包含在康奈尔大学-GHESKIO的艾滋病毒研究和临床合作活动中，包括：艾滋病毒疫苗和抗逆转录病毒临床试验的艾滋病毒临床试验单位(CTU)；世卫组织/TDR结核病和梅毒研究；联合国全球艾滋病、结核病和疟疾基金；总统艾滋病紧急救援计划(PEPFAR)；艾滋病综合国际方案研究(CIPRA)；国际艾滋病临床操作卫生服务研究培训(ICOHRTA)；加勒比、中美洲和南美洲网络(CCASAnet)；以及跨加勒比艾滋病毒/艾滋病研究倡议(TCHARI)。将高度重视为海地和加勒比地区开展艾滋病毒疫苗和临床试验以及业务和卫生研究项目提供便利的培训。除了在海地的研究培训外，学员还将有机会与杰出的美国导师一起接受高级培训。该计划的美国核心和合作培训教师由致力于艾滋病研究的科学家资助。教职员工构成了一个凝聚力很强的团队，他们的兴趣各不相同，但各有侧重。

DESCRIPTION (provided by applicant): This proposal requests support for Weill Cornell Medical College (WMC or Cornell) to continue training Haitian scientists in the performance of biomedical, epidemiological, laboratory, clinical, operational, health services and behavioral research on HIV and related opportunistic infections. The program is based in the Division of International Medicine and Infectious Diseases at Cornell, with an interdisciplinary group of investigators who have extensive collaborations with Haiti. Strengthened collaborations with Vanderbilt, Harvard, University of California (Berkeley), the Hastings Center, and the Aaron Diamond AIDS Research Center offer diverse training opportunities. The program will continue to emphasize medium and long-term advanced research training in Haiti. Since its inception, the AITRP program has provided medium- and long-term training to 121 Haitian biomedical personnel, with 98% currently conducting HIV/AIDS work in Haiti. The training offered will be related to six general HIV/AIDS research categories: 1) HIV vaccine trials; 2) antiretroviral clinical trials; 3) pediatrics and maternal-infant transmission research; 4) HIVassociated opportunistic infections - tuberculosis and human papilloma virus infection (HPV); 5) ethics and behavioral research, with an emphasis on adolescents; and 7) pathogenesis, immunology, and virology. The proposed training will be conducted largely in Haiti, with much of the training done by the former Fogarty trainees. The training program is imbedded in the ongoing collaborative Cornell-GHESKIO HIV research and clinical activities, including the following: HIV Clinical Trials Unit (CTU) for HIV vaccine and antiretroviral clinical trials; WHO/TDR tuberculosis and syphilis research; United Nations Global Fund for AIDS, Tuberculosis and Malaria; President's Emergency Plan for AIDS Relief (PEPFAR); Comprehensive International Program Research on AIDS (CIPRA); International Clinical Operational Health Services Research Training on AIDS (ICOHRTA); Caribbean, Central, and South America Network (CCASAnet); and the Trans-Caribbean HIV/AIDS Research Initiative (TCHARI). A high priority will be given to training that will facilitate the conduct of HIV vaccine and clinical trials, and operational and health research programs in Haiti and the Caribbean. In addition to research training in Haiti, trainees will have the opportunity for advanced training with outstanding US mentors. The program's US core and collaborating training faculty are funded scientists committed to AIDS research. The faculty constitutes a cohesive unit, with diverse but focused interests.